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. 1983 Sep;155(3):989–994. doi: 10.1128/jb.155.3.989-994.1983

Spectinomycin resistance due to a mutation in an rRNA operon of Escherichia coli.

L G Mark, C D Sigmund, E A Morgan
PMCID: PMC217790  PMID: 6193099

Abstract

A spectinomycin resistance mutation was isolated in an Escherichia coli rRNA operon (rrnH) located on a multicopy plasmid. Cell-free protein-synthesizing extracts made from cells containing the plasmid were partially resistant to spectinomycin. Although spectinomycin is an aminoglycoside antibiotic, the mutation did not confer resistance to any other aminoglycoside antibiotic tested.

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Selected References

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