Abstract
Anabaena sp. strain 6411, which produces the dihydroxamate siderophore schizokinen to facilitate iron uptake, is also capable of using the related siderophore aerobactin. The two siderophores compete for the same iron transport system, but there is a markedly higher affinity for ferric schizokinen than for ferric aerobactin. The trihydroxamate siderophore ferrioxamine B is far less effective as an iron donor in this organism. Anabaena sp. strain 7120 appears to be closely related to strain 6411. It synthesizes schizokinen as its major siderophore and shows rates of iron uptake from ferric schizokinen, ferric aerobactin, and ferrioxamine B which are similar to those observed with strain 6411. Anabaena cylindrica Lemm. 7122 and 1611, on the other hand, differ from strain 6411. In contrast to schizokinen, the hydroxamate which they produce in response to iron starvation cannot be extracted with water from the organic layer and does not support the growth of the siderophore auxotroph Arthrobacter flavescens JG-9. Strain 7122 can use its endogenous siderophore or schizokinen to promote iron uptake, but at 50-fold-lower rates than are observed with Anabaena sp. strain 6411 or 7120.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Akers H. A. Isolation of the siderophore schizokinen from soil of rice fields. Appl Environ Microbiol. 1983 May;45(5):1704–1706. doi: 10.1128/aem.45.5.1704-1706.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Haydon A. H., Davis W. B., Arceneaux J. E., Byers B. R. Hydroxamate recognition during iron transport from hydroxamate-ion chelates. J Bacteriol. 1973 Sep;115(3):912–918. doi: 10.1128/jb.115.3.912-918.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Lammers P. J., Sanders-Loehr J. Active transport of ferric schizokinen in Anabaena sp. J Bacteriol. 1982 Jul;151(1):288–294. doi: 10.1128/jb.151.1.288-294.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Mullis K. B., Pollack J. R., Neilands J. B. Structure of schizokinen, an iron-transport compound from Bacillus megaterium. Biochemistry. 1971 Dec 21;10(26):4894–4898. doi: 10.1021/bi00802a010. [DOI] [PubMed] [Google Scholar]
- Murphy T. P., Lean D. R., Nalewajko C. Blue-green algae: their excretion of iron-selective chelators enables them to dominate other algae. Science. 1976 May 28;192(4242):900–902. doi: 10.1126/science.818707. [DOI] [PubMed] [Google Scholar]
- Neilands J. B. Iron absorption and transport in microorganisms. Annu Rev Nutr. 1981;1:27–46. doi: 10.1146/annurev.nu.01.070181.000331. [DOI] [PubMed] [Google Scholar]
- Neilands J. B. Microbial envelope proteins related to iron. Annu Rev Microbiol. 1982;36:285–309. doi: 10.1146/annurev.mi.36.100182.001441. [DOI] [PubMed] [Google Scholar]
- Neilands J. B. Microbial iron compounds. Annu Rev Biochem. 1981;50:715–731. doi: 10.1146/annurev.bi.50.070181.003435. [DOI] [PubMed] [Google Scholar]