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. 1983 Dec;156(3):1198–1203. doi: 10.1128/jb.156.3.1198-1203.1983

Regulatory pattern of the Escherichia coli lysA gene: expression of chromosomal lysA-lacZ fusions.

P Stragier, F Borne, F Richaud, C Richaud, J C Patte
PMCID: PMC217968  PMID: 6417111

Abstract

The regulation of lysA which encodes the last enzyme for lysine biosynthesis in Escherichia coli, diaminopimelic acid-decarboxylase, was studied by using lysA-lacZ fusions. Our results indicate an absolute requirement for the LysR product for its activation, LysR protein present in a limiting amount which can be titrated by a multicopy plasmid carrying its target site and a negative regulatory role for the LysA protein itself which decreases lysA-lacZ expression 30-fold.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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