Abstract
The extrachromosomal psi+ determinant in the yeast Saccharomyces cerevisiae enhanced the expression of Mendelian UAA suppressors by 6- to 10-fold. The psi+ determinant by itself is a weak UAA suppressor that caused the production of approximately 1% of the normal level of iso-1-cytochrome c in a strain containing the UAA mutation cycl-72.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Culbertson M. R., Charnas L., Johnson M. T., Fink G. R. Frameshifts and frameshift suppressors in Saccharomyces cerevisiae. Genetics. 1977 Aug;86(4):745–764. doi: 10.1093/genetics/86.4.745. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Downie J. A., Stewart J. W., Brockman N., Schweingruber A. M., Sherman F. Structural gene for yeast iso-2-cytochrome c. J Mol Biol. 1977 Jun 25;113(2):369–384. doi: 10.1016/0022-2836(77)90147-4. [DOI] [PubMed] [Google Scholar]
- Sherman F., Stewart J. W. Genetics and biosynthesis of cytochrome c. Annu Rev Genet. 1971;5:257–296. doi: 10.1146/annurev.ge.05.120171.001353. [DOI] [PubMed] [Google Scholar]
- Sherman F., Taber H., Campbell W. Genetic determination of iso-cytochromes c in yeast. J Mol Biol. 1965 Aug;13(1):21–39. doi: 10.1016/s0022-2836(65)80077-8. [DOI] [PubMed] [Google Scholar]
- Stewart J. W., Sherman F. Demonstration of UAG as a nonsense codon in bakers' yeast by amino-acid replacements in iso-1-cytochrome c. J Mol Biol. 1972 Jul 28;68(3):429–443. doi: 10.1016/0022-2836(72)90097-6. [DOI] [PubMed] [Google Scholar]
- Stewart J. W., Sherman F., Shipman N. A., Jackson M. Identification and mutational relocation of the AUG codon initiating translation of iso-1-cytochrome c in yeast. J Biol Chem. 1971 Dec 25;246(24):7429–7445. [PubMed] [Google Scholar]
- Young C. S., Cox B. S. Extrachromosomal elements in a super-suppression system of yeast. II. Relations with other extrachromosomal elements. Heredity (Edinb) 1972 Apr;28(2):189–199. doi: 10.1038/hdy.1972.24. [DOI] [PubMed] [Google Scholar]