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. 1977 Jul 1;146(1):271–276. doi: 10.1084/jem.146.1.271

Preleukemic expression of TL antigens in x-irradiated C57BL/6 mice

PMCID: PMC2180749  PMID: 195001

Abstract

Anomalous appearance of TL (thymus-leukemia) antigens is a characteristic feature of radiation-induced leukemias of C57bl/6 mice. We now report that thymocytes of irradiated C57BL/6 mice express TL antigens long before the development of overt leukemia. Thus, TL is a marker for preleukemic changes occurring during radiation leukemogenesis. Low levels of murine leukemia virus (MuLV)-related antigens are also detected on preleukemic thymocytes. Comparative tests on individual mice show no direct correlation between TL and MuLV antigen expression.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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