Abstract
A shift to 42°C in an nrdA mutant causes a decrease in deoxyribonucleic acid synthesis without a concomitant decrease in deoxynucleotide triphosphate pools.
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Selected References
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- Alberts B., Sternglanz R. Recent excitement in the DNA replication problem. Nature. 1977 Oct 20;269(5630):655–661. doi: 10.1038/269655a0. [DOI] [PubMed] [Google Scholar]
- Collinsworth W. L., Mathews C. K. Biochemistry of DNA-defective amber mutants of bacteriophage T4. IV. DNA synthesis in plasmolyzed cells. J Virol. 1974 Apr;13(4):908–915. doi: 10.1128/jvi.13.4.908-915.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Dermody J. J., Bourguignon G. J., Foglesong P. D., Sternglanz R. Nalidixic acid-sensitive and resistant modes of DNA replication in Escherichia coli. Biochem Biophys Res Commun. 1974 Dec 23;61(4):1340–1347. doi: 10.1016/s0006-291x(74)80431-6. [DOI] [PubMed] [Google Scholar]
- Dicou L., Cozzarelli N. R. Bacteriophage T4-directed DNA synthesis in toluene-treated cells. J Virol. 1973 Dec;12(6):1293–1302. doi: 10.1128/jvi.12.6.1293-1302.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Eriksson S. Ribonucleotide reductase from Escherichia coli: demonstration of a highly active form of the enzyme. Eur J Biochem. 1975 Aug 1;56(1):289–294. doi: 10.1111/j.1432-1033.1975.tb02232.x. [DOI] [PubMed] [Google Scholar]
- Eriksson S., Sjöberg B. M., Hahne S. Ribonucleoside diphosphate reductase from Escherichia coli. An immunological assay and a novel purification from an overproducing strain lysogenic for phage lambdadnrd. J Biol Chem. 1977 Sep 10;252(17):6132–6138. [PubMed] [Google Scholar]
- Filpula D., Fuchs J. A. Regulation of the synthesis of ribonucleoside diphosphate reductase in Escherichia coli: specific activity of the enzyme in relationship to perturbations of DNA replication. J Bacteriol. 1978 Aug;135(2):429–435. doi: 10.1128/jb.135.2.429-435.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Fridland A. DNA precursors in eukaryotic cells. Nat New Biol. 1973 May 23;243(125):105–107. [PubMed] [Google Scholar]
- Fuchs J. A., Karlström H. O. Mapping of nrdA and nrdB in Escherichia coli K-12. J Bacteriol. 1976 Dec;128(3):810–814. doi: 10.1128/jb.128.3.810-814.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Fuchs J. A., Karlström H. O., Warner H. R., Reichard P. Defective gene product in dnaF mutant of Escherichia coli. Nat New Biol. 1972 Jul 19;238(81):69–71. doi: 10.1038/newbio238069a0. [DOI] [PubMed] [Google Scholar]
- Kornberg T., Lockwood A., Worcel A. Replication of the Escherichia coli chromosome with a soluble enzyme system. Proc Natl Acad Sci U S A. 1974 Aug;71(8):3189–3193. doi: 10.1073/pnas.71.8.3189. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Larsson A., Reichard P. Allosteric effects and substrate specificity of the ribonucleoside diphosphate reductase system from Escherichia coli B. Biochim Biophys Acta. 1966 Feb 14;113(2):407–408. doi: 10.1016/s0926-6593(66)80083-8. [DOI] [PubMed] [Google Scholar]
- Manwaring J. D., Fuchs J. A. Nucleoside triphosphate pools in minicells of Escherichia coli. J Bacteriol. 1977 May;130(2):960–962. doi: 10.1128/jb.130.2.960-962.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
- North T. W., Stafford M. E., Mathews C. K. Biochemistry of DNA-defective mutants of bacteriophage T4. VI. Biological functions of gene 42. J Virol. 1976 Mar;17(3):973–982. doi: 10.1128/jvi.17.3.973-982.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
- PRITCHARD R. H., LARK K. G. INDUCTION OF REPLICATION BY THYMINE STARVATION AT THE CHROMOSOME ORIGIN IN ESCHERICHIA COLI. J Mol Biol. 1964 Aug;9:288–307. doi: 10.1016/s0022-2836(64)80208-4. [DOI] [PubMed] [Google Scholar]
- Reddy G. P., Singh A., Stafford M. E., Mathews C. K. Enzyme associations in T4 phage DNA precursor synthesis. Proc Natl Acad Sci U S A. 1977 Aug;74(8):3152–3156. doi: 10.1073/pnas.74.8.3152. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Schekman R., Weiner A., Kornberg A. Multienzyme systems of DNA replication. Science. 1974 Dec 13;186(4168):987–993. doi: 10.1126/science.186.4168.987. [DOI] [PubMed] [Google Scholar]
- Vosberg H. P., Hoffmann-Berling H. DNA synthesis in nucleotide-permeable Escherichia coli cells. I. Preparation and properties of ether-treated cells. J Mol Biol. 1971 Jun 28;58(3):739–753. doi: 10.1016/0022-2836(71)90037-4. [DOI] [PubMed] [Google Scholar]
- Warner H. R. Properties of ribonucleoside diphosphate reductase in nucleotide-permeable cells. J Bacteriol. 1973 Jul;115(1):18–22. doi: 10.1128/jb.115.1.18-22.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Wechsler J. A., Gross J. D. Escherichia coli mutants temperature-sensitive for DNA synthesis. Mol Gen Genet. 1971;113(3):273–284. doi: 10.1007/BF00339547. [DOI] [PubMed] [Google Scholar]
- Wickner W., Schekman R., Geider K., Kornberg A. A new form of DNA polymerase 3 and a copolymerase replicate a long, single-stranded primer-template. Proc Natl Acad Sci U S A. 1973 Jun;70(6):1764–1767. doi: 10.1073/pnas.70.6.1764. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Wovcha M. G., Tomich P. K., Chiu C. S., Greenberg G. R. Direct participation of dCMP hydroxymethylase in synthesis of bacteriophage T4 DNA. Proc Natl Acad Sci U S A. 1973 Aug;70(8):2196–2200. doi: 10.1073/pnas.70.8.2196. [DOI] [PMC free article] [PubMed] [Google Scholar]
