Abstract
The synthesis of teichoic acids was examined in Bacillus subtilis Marburg grown under conditions of phosphate limitation. The results indicate that the inhibition of polyglycerolphosphate synthesis observed under these conditions is the result of two processes. The first process is reversible and is independent of new protein synthesis; the second process is irreversible and requires the synthesis of new protein. During growth, under conditions of phosphate limitation, there is a slow decrease in the level of CDP glycerol pyrophosphorylase activity which is by itself not sufficient to account for the decrease in the rate of polyglycerolphosphate synthesis.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- BURGER M. M., GLASER L. THE SYNTHESIS OF TEICHOIC ACIDS. I. POLYGLYCEROPHOSPHATE. J Biol Chem. 1964 Oct;239:3168–3177. [PubMed] [Google Scholar]
- Bracha R., Chang M., Fiedler F., Glaser L. Biosynthesis of teichoic acids. Methods Enzymol. 1978;50:387–340. doi: 10.1016/0076-6879(78)50046-3. [DOI] [PubMed] [Google Scholar]
- GLASER L. THE SYNTHESIS OF TEICHOIC ACID. IV. ON THE REGULATION OF CYTIDINE 5'-DIPHOSPHATEGLYCEROL CONCENTRATION. Biochim Biophys Acta. 1965 Mar 1;101:6–15. doi: 10.1016/0926-6534(65)90025-4. [DOI] [PubMed] [Google Scholar]
- Glaser L., Melo A., Paul R. Uridine diphosphate sugar hydrolase. Purification of enzyme and protein inhibitor. J Biol Chem. 1967 Apr 25;242(8):1944–1954. [PubMed] [Google Scholar]
- Hussey H., Sueda S., Cheah S. C., Baddiley J. Control of teichoic acid synthesis in Bacillus licheniformis ATCC 9945. Eur J Biochem. 1978 Jan 2;82(1):169–174. doi: 10.1111/j.1432-1033.1978.tb12008.x. [DOI] [PubMed] [Google Scholar]
- LOWRY O. H., ROSEBROUGH N. J., FARR A. L., RANDALL R. J. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951 Nov;193(1):265–275. [PubMed] [Google Scholar]
- Lowry O. H., Carter J., Ward J. B., Glaser L. The effect of carbon and nitrogen sources on the level of metabolic intermediates in Escherichia coli. J Biol Chem. 1971 Nov;246(21):6511–6521. [PubMed] [Google Scholar]
- Mauck J., Glaser L. On the mode of in vivo assembly of the cell wall of Bacillus subtilis. J Biol Chem. 1972 Feb 25;247(4):1180–1187. [PubMed] [Google Scholar]
- Mauck J., Glaser L. Periplasmic nucleoside diphosphate sugar hydrolase from Bacillus subtilis. Biochemistry. 1970 Mar 3;9(5):1140–1147. doi: 10.1021/bi00807a014. [DOI] [PubMed] [Google Scholar]
- Mindich L. Membrane synthesis in Bacillus subtilis. I. Isolation and properties of strains bearing mutations in glycerol metabolism. J Mol Biol. 1970 Apr 28;49(2):415–432. doi: 10.1016/0022-2836(70)90254-8. [DOI] [PubMed] [Google Scholar]
- Mueller K., Bremer H. Rate of synthesis of messenger ribonucleic acid in Escherichia coli. J Mol Biol. 1968 Dec;38(3):329–353. doi: 10.1016/0022-2836(68)90390-2. [DOI] [PubMed] [Google Scholar]
- Pooley H. M. Layered distribution, according to age, within the cell wall of bacillus subtilis. J Bacteriol. 1976 Mar;125(3):1139–1147. doi: 10.1128/jb.125.3.1139-1147.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Rosenberger R. F. Control of teichoic and teichuronic acid biosynthesis in Bacillus subtilis 168trp. Evidence for repression of enzyme synthesis and inhibition of enzyme activity. Biochim Biophys Acta. 1976 Apr 23;428(2):516–524. doi: 10.1016/0304-4165(76)90060-x. [DOI] [PubMed] [Google Scholar]