Abstract
The mannans from Candida albicans strains NIH A-207 (serotype A), NIH B-792 (serotype B), and J-1012 (serotype C) were fractionated on a column of diethylaminoethyl-Sephadex into five subfractions containing different amounts of phosphate. Antibody-precipitating activities of the mannan subfractions of strains NIH A-207 and NIH B-792 were proportional to their phosphate content, while those of strain J-1012 did not show regularly proportional precipitin activity. A similar tendency was also observed in the cross-reaction between the mannan su,fractions of strains NIH A-207 and J-1012 and their heterologous antisera. The mannans of strain NIH B-792 showed lower cross-reactivities against antisera of strains NIH A-207 and NIH B-792, i.e., only two subfractions containing larger amounts of phosphate were able to react with these antisera.
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- AMES B. N., DUBIN D. T. The role of polyamines in the neutralization of bacteriophage deoxyribonucleic acid. J Biol Chem. 1960 Mar;235:769–775. [PubMed] [Google Scholar]
- Colonna W. J., Lampen J. O. Structure of the mannan form Saccharomyces strain FH4C, a mutant constitutive for invertase biosynthesis. I. Significance of phosphate to the structure and refractoriness of the molecule. Biochemistry. 1974 Jun 18;13(13):2741–2748. doi: 10.1021/bi00710a013. [DOI] [PubMed] [Google Scholar]
- HASENCLEVER H. F., MITCHELL W. O., LOEWE J. Antigenic studies of Candida. II. Antigenic relation of Candida albicans group A and group B to Candida stellatoidea and Candida tropicalis. J Bacteriol. 1961 Oct;82:574–577. doi: 10.1128/jb.82.4.574-577.1961. [DOI] [PMC free article] [PubMed] [Google Scholar]
- LOWRY O. H., ROSEBROUGH N. J., FARR A. L., RANDALL R. J. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951 Nov;193(1):265–275. [PubMed] [Google Scholar]
- Lloyd K. O. Isolation, characterization, and partial structure of peptido galactomannans from the yeast form of Cladosporium werneckii. Biochemistry. 1970 Aug 18;9(17):3446–3453. doi: 10.1021/bi00819a025. [DOI] [PubMed] [Google Scholar]
- Okubo Y., Ichikawa T., Suzuki S. Relationship between phosphate content and immunochemical properties of subfractions of bakers' yeast mannan. J Bacteriol. 1978 Oct;136(1):63–68. doi: 10.1128/jb.136.1.63-68.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sunayama H. Studies on the antigenic activities of yeasts. IV. Analysis of the antigenic determinant groups of the mannan of Candida albicans serotype A. Jpn J Microbiol. 1970 Jan;14(1):27–39. doi: 10.1111/j.1348-0421.1970.tb00488.x. [DOI] [PubMed] [Google Scholar]
- Thieme T. R., Ballou C. E. Nature of the phosphodiester linkage of the phosphomannan from the yeast Kloeckera brevis. Biochemistry. 1971 Oct 26;10(22):4121–4129. doi: 10.1021/bi00798a017. [DOI] [PubMed] [Google Scholar]