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. 1981 Aug 1;154(2):541–546. doi: 10.1084/jem.154.2.541

Specificity of the helper T cell for the cytolytic T lymphocyte response to influenza viruses

CS Reiss, SJ Burakoff
PMCID: PMC2186412  PMID: 6973607

Abstract

We have described a model system in which helper T cells are required to mount a primary antiviral cytolytic T lymphocyte response. The radioresistant helper cell can be found in the spleens of mice that have been immunized subcutaneously with influenza viruses 6-8 d previously. These helper cells appear to be type specific but cross-reactive among the subtypes of influenza A viruses. The phenotypes of the interacting cell populations were determined.

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Selected References

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