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. 1982 Oct 1;156(4):1131–1148. doi: 10.1084/jem.156.4.1131

Mutant monoclonal antibodies with alterations in biological functions

DE Yelton, MD Scharff
PMCID: PMC2186830  PMID: 6818317

Abstract

Somatic cell mutants with deletions in the immunoglobulin constant region were isolated from an IgG(2b) Ar-binding hybridoma. Rat anti-mouse immunoglobulins were used to identify the sites of the deletions. The mutant monoclonal antibodies differ from the parental molecule in their assembly states and are defective in various immunoglobulin activities, making them potentially more useful reagents.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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