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. 1983 Apr 1;157(4):1197–1207. doi: 10.1084/jem.157.4.1197

Antibody response of immunodeficient (xid) CBA/N mice to Escherichia coli 0113 lipopolysaccharide, a thymus-independent antigen

PMCID: PMC2186980  PMID: 6187886

Abstract

CBA/N mice, which possess an X-linked immunodeficiency (xid), produce a convincing antibody response to lipopolysaccharide derived from Escherichia coli 0113 (LPS 0113), a thymus-independent antigen. The antibody response produced was shown to be specific for the O- polysaccharide moiety of LPS 0113, rather than lipid A or lipid-A- associated protein. The relevance of this finding to the nature of the genetic defect of xid-mice is discussed.

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Selected References

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