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. 1984 Jun 1;159(6):1778–1783. doi: 10.1084/jem.159.6.1778

Sendai virus-specific T cell clones. V. Induction of a virus-specific response by antiidiotypic antibodies directed against a T helper cell clone

PMCID: PMC2187327  PMID: 6327875

Abstract

We used an antiidiotypic antibody directed against a Sendai virus- specific T helper cell clone to stimulate an immune response in vivo. In addition, the antiidiotypic antibody induced T cells that mediated a delayed-type hypersensitivity (DTH) response in several different mouse strains. Induction of the DTH response by the antiidiotypic antibody, in contrast to the DTH responses induced by virus, demonstrated a remarkable lack of H-2 restriction.

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Selected References

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