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. 1987 Dec 1;166(6):1900–1905. doi: 10.1084/jem.166.6.1900

Isolation and characterization of a light chain variable region gene for human rheumatoid factors

PMCID: PMC2188786  PMID: 3119763

Abstract

Previously, we isolated a Vk gene (Humkv325) from a human placenta that encodes RF light chains bearing the PSL2 and PSL3 CRI markers. Here we report the isolation and characterization of a second human Vk gene (Humkv328) that can be used for RF synthesis. This Vk gene probably encodes at least two 6B6.6 CRI+ RF light chains (Les and Pom) from unrelated subjects, and thus may be related to the light chain- associated 6B6.6 CRI.

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Selected References

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