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. 1976 Jul 1;144(1):282–287. doi: 10.1084/jem.144.1.282

Association between Ia antigens and the Fc receptors of certain T lymphocytes

PMCID: PMC2190367  PMID: 1084408

Abstract

The Fc receptors of thymic and splenic T lymphocytes were detected using indirect immunofluorescence and soluble antigen-antibody complexes. 10-20% of thymocytes and 40-50% of Thy-1-positive splenic lymphocytes bound antigen-complexed Ig. The binding to thymocytes was partially inhibited (45-74%) by antibodies against antigens determined by the I region of the H-2 complex, but not by antibodies against K- or D-region antigens or Thy-1 antigen. The inhibition did not require the Fc portion of the inhibiting antibody. These results provide evidence that Ia antigens and the Fc receptors of some T lymphocytes are associated, and that the populations of T cells which bear these moieties at least partially overlap.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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