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. 1996 Mar 1;183(3):721–724. doi: 10.1084/jem.183.3.721

Fas and the art of lymphocyte maintenance

PMCID: PMC2192341  PMID: 8642275

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Selected References

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  1. Banner D. W., D'Arcy A., Janes W., Gentz R., Schoenfeld H. J., Broger C., Loetscher H., Lesslauer W. Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation. Cell. 1993 May 7;73(3):431–445. doi: 10.1016/0092-8674(93)90132-a. [DOI] [PubMed] [Google Scholar]
  2. Boehme S. A., Lenardo M. J. Propriocidal apoptosis of mature T lymphocytes occurs at S phase of the cell cycle. Eur J Immunol. 1993 Jul;23(7):1552–1560. doi: 10.1002/eji.1830230724. [DOI] [PubMed] [Google Scholar]
  3. Broome H. E., Dargan C. M., Krajewski S., Reed J. C. Expression of Bcl-2, Bcl-x, and Bax after T cell activation and IL-2 withdrawal. J Immunol. 1995 Sep 1;155(5):2311–2317. [PubMed] [Google Scholar]
  4. Bruno L., Kirberg J., von Boehmer H. On the cellular basis of immunological T cell memory. Immunity. 1995 Jan;2(1):37–43. doi: 10.1016/1074-7613(95)90077-2. [DOI] [PubMed] [Google Scholar]
  5. Cascino I., Fiucci G., Papoff G., Ruberti G. Three functional soluble forms of the human apoptosis-inducing Fas molecule are produced by alternative splicing. J Immunol. 1995 Mar 15;154(6):2706–2713. [PubMed] [Google Scholar]
  6. Cheng G., Cleary A. M., Ye Z. S., Hong D. I., Lederman S., Baltimore D. Involvement of CRAF1, a relative of TRAF, in CD40 signaling. Science. 1995 Mar 10;267(5203):1494–1498. doi: 10.1126/science.7533327. [DOI] [PubMed] [Google Scholar]
  7. Cheng J., Zhou T., Liu C., Shapiro J. P., Brauer M. J., Kiefer M. C., Barr P. J., Mountz J. D. Protection from Fas-mediated apoptosis by a soluble form of the Fas molecule. Science. 1994 Mar 25;263(5154):1759–1762. doi: 10.1126/science.7510905. [DOI] [PubMed] [Google Scholar]
  8. Cleveland J. L., Ihle J. N. Contenders in FasL/TNF death signaling. Cell. 1995 May 19;81(4):479–482. doi: 10.1016/0092-8674(95)90068-3. [DOI] [PubMed] [Google Scholar]
  9. Cosman D. A family of ligands for the TNF receptor superfamily. Stem Cells. 1994 Sep;12(5):440–455. doi: 10.1002/stem.5530120501. [DOI] [PubMed] [Google Scholar]
  10. Dhein J., Walczak H., Bäumler C., Debatin K. M., Krammer P. H. Autocrine T-cell suicide mediated by APO-1/(Fas/CD95) Nature. 1995 Feb 2;373(6513):438–441. doi: 10.1038/373438a0. [DOI] [PubMed] [Google Scholar]
  11. Duke R. C., Cohen J. J. IL-2 addiction: withdrawal of growth factor activates a suicide program in dependent T cells. Lymphokine Res. 1986 Fall;5(4):289–299. [PubMed] [Google Scholar]
  12. Fisher G. H., Rosenberg F. J., Straus S. E., Dale J. K., Middleton L. A., Lin A. Y., Strober W., Lenardo M. J., Puck J. M. Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome. Cell. 1995 Jun 16;81(6):935–946. doi: 10.1016/0092-8674(95)90013-6. [DOI] [PubMed] [Google Scholar]
  13. Golstein P., Marguet D., Depraetere V. Homology between reaper and the cell death domains of Fas and TNFR1. Cell. 1995 Apr 21;81(2):185–186. doi: 10.1016/0092-8674(95)90327-5. [DOI] [PubMed] [Google Scholar]
  14. Lenardo M. J., Boehme S., Chen L., Combadiere B., Fisher G., Freedman M., McFarland H., Pelfrey C., Zheng L. Autocrine feedback death and the regulation of mature T lymphocyte antigen responses. Int Rev Immunol. 1995;13(2):115–134. doi: 10.3109/08830189509061742. [DOI] [PubMed] [Google Scholar]
  15. Lenardo M. J. Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis. Nature. 1991 Oct 31;353(6347):858–861. doi: 10.1038/353858a0. [DOI] [PubMed] [Google Scholar]
  16. Matsumoto K., Schleimer R. P., Saito H., Iikura Y., Bochner B. S. Induction of apoptosis in human eosinophils by anti-Fas antibody treatment in vitro. Blood. 1995 Aug 15;86(4):1437–1443. [PubMed] [Google Scholar]
  17. Nagata S., Golstein P. The Fas death factor. Science. 1995 Mar 10;267(5203):1449–1456. doi: 10.1126/science.7533326. [DOI] [PubMed] [Google Scholar]
  18. Rathmell J. C., Cooke M. P., Ho W. Y., Grein J., Townsend S. E., Davis M. M., Goodnow C. C. CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+ T cells. Nature. 1995 Jul 13;376(6536):181–184. doi: 10.1038/376181a0. [DOI] [PubMed] [Google Scholar]
  19. Reap E. A., Felix N. J., Wolthusen P. A., Kotzin B. L., Cohen P. L., Eisenberg R. A. bcl-2 transgenic Lpr mice show profound enhancement of lymphadenopathy. J Immunol. 1995 Dec 1;155(11):5455–5462. [PubMed] [Google Scholar]
  20. Reap E. A., Leslie D., Abrahams M., Eisenberg R. A., Cohen P. L. Apoptosis abnormalities of splenic lymphocytes in autoimmune lpr and gld mice. J Immunol. 1995 Jan 15;154(2):936–943. [PubMed] [Google Scholar]
  21. Rieux-Laucat F., Le Deist F., Hivroz C., Roberts I. A., Debatin K. M., Fischer A., de Villartay J. P. Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity. Science. 1995 Jun 2;268(5215):1347–1349. doi: 10.1126/science.7539157. [DOI] [PubMed] [Google Scholar]
  22. Rothe M., Wong S. C., Henzel W. J., Goeddel D. V. A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor. Cell. 1994 Aug 26;78(4):681–692. doi: 10.1016/0092-8674(94)90532-0. [DOI] [PubMed] [Google Scholar]
  23. Russell J. H., Rush B., Weaver C., Wang R. Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide. Proc Natl Acad Sci U S A. 1993 May 15;90(10):4409–4413. doi: 10.1073/pnas.90.10.4409. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Simon H. U., Yousefi S., Dommann-Scherrer C. C., Zimmermann D. R., Bauer S., Barandun J., Blaser K. Expansion of cytokine-producing CD4-CD8- T cells associated with abnormal Fas expression and hypereosinophilia. J Exp Med. 1996 Mar 1;183(3):1071–1082. doi: 10.1084/jem.183.3.1071. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. Smith C. A., Farrah T., Goodwin R. G. The TNF receptor superfamily of cellular and viral proteins: activation, costimulation, and death. Cell. 1994 Mar 25;76(6):959–962. doi: 10.1016/0092-8674(94)90372-7. [DOI] [PubMed] [Google Scholar]
  26. Sneller M. C., Straus S. E., Jaffe E. S., Jaffe J. S., Fleisher T. A., Stetler-Stevenson M., Strober W. A novel lymphoproliferative/autoimmune syndrome resembling murine lpr/gld disease. J Clin Invest. 1992 Aug;90(2):334–341. doi: 10.1172/JCI115867. [DOI] [PMC free article] [PubMed] [Google Scholar]
  27. Tartaglia L. A., Ayres T. M., Wong G. H., Goeddel D. V. A novel domain within the 55 kd TNF receptor signals cell death. Cell. 1993 Sep 10;74(5):845–853. doi: 10.1016/0092-8674(93)90464-2. [DOI] [PubMed] [Google Scholar]
  28. Theofilopoulos A. N., Dixon F. J. Murine models of systemic lupus erythematosus. Adv Immunol. 1985;37:269–390. doi: 10.1016/s0065-2776(08)60342-9. [DOI] [PubMed] [Google Scholar]
  29. Wu J., Zhou T., Zhang J., He J., Gause W. C., Mountz J. D. Correction of accelerated autoimmune disease by early replacement of the mutated lpr gene with the normal Fas apoptosis gene in the T cells of transgenic MRL-lpr/lpr mice. Proc Natl Acad Sci U S A. 1994 Mar 15;91(6):2344–2348. doi: 10.1073/pnas.91.6.2344. [DOI] [PMC free article] [PubMed] [Google Scholar]
  30. Zheng L., Fisher G., Miller R. E., Peschon J., Lynch D. H., Lenardo M. J. Induction of apoptosis in mature T cells by tumour necrosis factor. Nature. 1995 Sep 28;377(6547):348–351. doi: 10.1038/377348a0. [DOI] [PubMed] [Google Scholar]

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