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The Journal of General Physiology logoLink to The Journal of General Physiology
. 1961 Jul 1;44(6):1055–1057. doi: 10.1085/jgp.44.6.1055

Non-Linear Current-Potential Relations in an Axon Membrane

Kenneth S Cole 1
PMCID: PMC2195148  PMID: 13694551

Abstract

The membrane current density, Im, in the squid giant axon has been calculated from the measured external current applied to the axon, Io, by the equation See PDF for Equation where Vm is the membrane potential under the current electrode and r1 and r2 are the external and internal longitudinal resistances. The original derivation of this equation included in one step an assumption of a linear relation between Im and Vm. It is shown that the same equation can be obtained without this restricting assumption.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. HODGKIN A. L., HUXLEY A. F. Movement of radioactive potassium and membrane current in a giant axon. J Physiol. 1953 Aug;121(2):403–414. doi: 10.1113/jphysiol.1953.sp004954. [DOI] [PMC free article] [PubMed] [Google Scholar]

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