Skip to main content
The Journal of General Physiology logoLink to The Journal of General Physiology
. 1962 Nov 1;46(2):189–199. doi: 10.1085/jgp.46.2.189

Cat Heart Muscle in Vitro

II. The steady state resting potential in quiescent papillary muscles

Ernest Page 1
PMCID: PMC2195263  PMID: 13941048

Abstract

The steady state transmembrane resting potential difference (Vm) has been measured in quiescent papillary muscles. Vm was determined as a function of the external K concentration in Cl and SO4 solutions and compared with the K equilibrium potential. Other measurements were made after replacement of external Na by choline, K by Rb and Cs, and Cl by SO4, CH3SO4, and NO3. Effects on Vm of albumin, temperature, and variation in internal K concentration are described.

Full Text

The Full Text of this article is available as a PDF (656.5 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ADRIAN R. H. The effect of internal and external potassium concentration on the membrane potential of frog muscle. J Physiol. 1956 Sep 27;133(3):631–658. doi: 10.1113/jphysiol.1956.sp005615. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. BURGEN A. S. V., TERROUX K. G. The membrane resting and action potentials of the cat auricle. J Physiol. 1953 Feb 27;119(2-3):139–152. doi: 10.1113/jphysiol.1953.sp004834. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. CARMELIET E. E. Chloride ions and the membrane potential of Purkinje fibres. J Physiol. 1961 Apr;156:375–388. doi: 10.1113/jphysiol.1961.sp006682. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. CORABOEUF E., OTSUKA M. L'action des solutions hyposodiques sur les potentiels cellulaires de tissu cardiaque de mammifères. C R Hebd Seances Acad Sci. 1956 Jul 23;243(4):441–444. [PubMed] [Google Scholar]
  5. DELEZE J. Perfusion of a strip of mammalian ventricle; effects of K-rich and Na-deficient solutions on transmembrane potentials. Circ Res. 1959 May;7(3):461–465. doi: 10.1161/01.res.7.3.461. [DOI] [PubMed] [Google Scholar]
  6. GREEN J. P., GIARMAN N. J., SALTER W. T. The action of serum protein fractions on the isolated mammalian myocardium. J Pharmacol Exp Ther. 1952 Nov;106(3):346–352. [PubMed] [Google Scholar]
  7. HODGKIN A. L., HOROWICZ P. The influence of potassium and chloride ions on the membrane potential of single muscle fibres. J Physiol. 1959 Oct;148:127–160. doi: 10.1113/jphysiol.1959.sp006278. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. HODGKIN A. L., KATZ B. The effect of sodium ions on the electrical activity of giant axon of the squid. J Physiol. 1949 Mar 1;108(1):37–77. doi: 10.1113/jphysiol.1949.sp004310. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. HUTTER O. F., NOBLE D. Anion conductance of cardiac muscle. J Physiol. 1961 Jul;157:335–350. doi: 10.1113/jphysiol.1961.sp006726. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. HUTTER O. F., NOBLE D. The chloride conductance of frog skeletal muscle. J Physiol. 1960 Apr;151:89–102. [PMC free article] [PubMed] [Google Scholar]
  11. PAGE E. Cat heart muscle in vitro. III. The extracellular space. J Gen Physiol. 1962 Nov;46:201–213. doi: 10.1085/jgp.46.2.201. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. PAGE E., SOLOMON A. K. Cat heart muscle in vitro. I. Cell volumes and intracellular concentrations in papillary muscle. J Gen Physiol. 1960 Nov;44:327–344. doi: 10.1085/jgp.44.2.327. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. SJODIN R. A. Rubidium and cesium fluxes in muscle as related to the membrane potential. J Gen Physiol. 1959 May 20;42(5):983–1003. doi: 10.1085/jgp.42.5.983. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from The Journal of General Physiology are provided here courtesy of The Rockefeller University Press

RESOURCES