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. 1963 Jul 1;46(6):1123–1140. doi: 10.1085/jgp.46.6.1123

Some Electrical Properties of a Nuclear Membrane Examined with a Microelectrode

Werner R Loewenstein 1,2, Yoshinobu Kanno 1,2
PMCID: PMC2195317  PMID: 14042995

Abstract

Electrical potential and resistance were measured with microelectrodes in in situ and isolated nuclei of gland cells of Drosophila flavorepleta. The nucleus-cytoplasm boundary was found to be rather impermeable to ion diffusion. It presents a resistance of the order of 1 Ω cm2 and sustains a "resting" potential, the nucleoplasm being about 15 mv negative with respect to the cytoplasm. Both the resistance and potential appear to be associated with the nuclear membrane: the potential declines to zero and the resistance to a fraction of its original value, when the membrane is perforated experimentally.

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Selected References

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