Table 2.

MoAb to CCL5 reduces T-cell proliferation in vitro

	CCL5*	CCL3†	CCL4†
Absolute reduction, cpm × 103	48.9	−4.2	−5.2
Reduction, %	77.7	−13.8	−17.1

The addition of anti-CCL5 MoAb significantly reduced allospecific proliferation of CCR1^+/+ wild-type T cells in vitro compared with isotype control (P < .05), whereas anti-CCL3 and anti-CCL4 MoAb did not. Data are presented as means plus or minus SEM and are from 1 of 3 similar experiments.

^*Based on reference T + DC + IgG of 62.9 ± 6.1 cpm × 10³.

^†Based on reference T + DC + IgG of 30.4 ± 1.3 cpm × 10³.