Skip to main content
The Journal of General Physiology logoLink to The Journal of General Physiology
. 1968 Apr 1;51(4):579–587. doi: 10.1085/jgp.51.4.579

Kinetic Analysis of the Permeability of Human Erythrocytes to NH4Cl

F R Hunter 1
PMCID: PMC2201160  PMID: 5651773

Abstract

A densimeter technique was used to make a kinetic analysis of the rate of swelling of human erythrocytes suspended in 1% NaCl following successive additions of NH4Cl. Two series of experiments were performed, one in the absence of and the other in the presence of 6 x 10-4 M NaHCO3. An analysis of the data using Widdas's equations gave a family of curves in each instance. When LeFevre's equation was used with a value of ø = 1.3 isotones, a straight line was obtained with both series of data. It is concluded that this system shows carrier kinetics.

Full Text

The Full Text of this article is available as a PDF (450.1 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Hunter F. R., George J., Ospina B. Possible carriers in erythrocytes. J Cell Physiol. 1965 Jun;65(3):299–311. doi: 10.1002/jcp.1030650303. [DOI] [PubMed] [Google Scholar]
  2. Jacobs M. H., Stewart D. R. THE ROLE OF CARBONIC ANHYDRASE IN CERTAIN IONIC EXCHANGES INVOLVING THE ERYTHROCYTE. J Gen Physiol. 1942 Mar 20;25(4):539–552. doi: 10.1085/jgp.25.4.539. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from The Journal of General Physiology are provided here courtesy of The Rockefeller University Press

RESOURCES