Abstract
Receptor units in the eye of the horseshoe crab are more sensitive to lateral inhibition at some levels of excitation than they are at others. As a result, the steady-state inhibition of the response of a given unit is not directly proportional to the response levels of neighboring units. This effect may be represented by the introduction of a nonlinearity in the Hartline-Ratliff system of equations. The nonlinear inhibitory effect appears to increase the operating range of the receptor units.
Full Text
The Full Text of this article is available as a PDF (609.7 KB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- BARLOW H. B., FITZHUGH R., KUFFLER S. W. Change of organization in the receptive fields of the cat's retina during dark adaptation. J Physiol. 1957 Aug 6;137(3):338–354. doi: 10.1113/jphysiol.1957.sp005817. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Barlow H. B., Levick W. R. Changes in the maintained discharge with adaptation level in the cat retina. J Physiol. 1969 Jun;202(3):699–718. doi: 10.1113/jphysiol.1969.sp008836. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Barlow R. B., Jr Inhibitory fields in the Limulus lateral eye. J Gen Physiol. 1969 Sep;54(3):383–396. doi: 10.1085/jgp.54.3.383. [DOI] [PMC free article] [PubMed] [Google Scholar]
- HARTLINE H. K., RATLIFF F. Inhibitory interaction of receptor units in the eye of Limulus. J Gen Physiol. 1957 Jan 20;40(3):357–376. doi: 10.1085/jgp.40.3.357. [DOI] [PMC free article] [PubMed] [Google Scholar]
- HARTLINE H. K., RATLIFF F. Spatial summation of inhibitory influences in the eye of Limulus, and the mutual interaction of receptor units. J Gen Physiol. 1958 May 20;41(5):1049–1066. doi: 10.1085/jgp.41.5.1049. [DOI] [PMC free article] [PubMed] [Google Scholar]
- HARTLINE H. K., WAGNER H. G., RATLIFF F. Inhibition in the eye of Limulus. J Gen Physiol. 1956 May 20;39(5):651–673. doi: 10.1085/jgp.39.5.651. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Knight B. W., Toyoda J. I., Dodge F. A., Jr A quantitative description of the dynamics of excitation and inhibition in the eye of Limulus. J Gen Physiol. 1970 Oct;56(4):421–437. doi: 10.1085/jgp.56.4.421. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Milkman N., Schoenfeld R. L. A digital programmer for stimuli and computer control in neurophysiological experiments. Ann N Y Acad Sci. 1966 Jan 31;128(3):861–875. doi: 10.1111/j.1749-6632.1965.tb11704.x. [DOI] [PubMed] [Google Scholar]
- SCHOENFELD R. L. THE ROLE OF A DIGITAL COMPUTER AS A BIOLOGICAL INSTRUMENT. Ann N Y Acad Sci. 1964 Jul 31;115:915–942. [PubMed] [Google Scholar]
- TOMITA T. Mechanism of lateral inhibition in eye of Limulus. J Neurophysiol. 1958 Sep;21(5):419–429. doi: 10.1152/jn.1958.21.5.419. [DOI] [PubMed] [Google Scholar]