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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1965 Apr;53(4):791–796. doi: 10.1073/pnas.53.4.791

AROMATIC AZO DERIVATIVES PREVENTING MAMMARY CANCER AND ADRENAL INJURY FROM 7,12-DIMETHYLBENZ(a)ANTHRACENE*

Charles Huggins 1, John Pataki 1
PMCID: PMC221068  PMID: 14324535

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ARCOS J. C., CONNEY A. H., BUU-HOI N. P. Induction of microsomal enzyme synthesis by polycyclic aromatic hydrocarbons of different molecular sizes. J Biol Chem. 1961 May;236:1291–1296. [PubMed] [Google Scholar]
  2. CURRIE A. R., HELFENSTEIN J. E., YOUNG S. Massive adrenal necrosis in rats caused by 9,10-dimethyl-1,2-benzanthracene and its inhibition by metyrapone. Lancet. 1962 Dec 8;2(7267):1199–1200. doi: 10.1016/s0140-6736(62)90966-2. [DOI] [PubMed] [Google Scholar]
  3. DAO T. L., TANAKA Y. INHIBITORY EFFECT OF POLYNUCLEAR HYDROCARBONS AND AMPHENONE ANALOGS ON INDUCTION OF ACUTE ADRENAL NECROSIS BY 7,12-DIMETHYLBENZ(ALPHA)ANTHRACENE. Cancer Res. 1963 Sep;23:1148–1152. [PubMed] [Google Scholar]
  4. HUGGINS C., DEUEL T. F., FUKUNISHI R. PROTECTION OF ADRENAL CORTEX BY HYDROCARBONS AGAINST INJURY FROM 7,12-DIMETHYLBENZ(A)ANTHRACENE. Biochem Z. 1963;338:106–113. [PubMed] [Google Scholar]
  5. HUGGINS C., FUKUNISHI R. INDUCED PROTECTION OF ADRENAL CORTEX AGAINST 7,12-DIMETHYLBENZ(ALPHA)ANTHRACENE. INFLUENCE OF ETHIONINE. INDUCTION OF MENADIONE REDUCTASE. INCORPORATION OF THYMIDINE-H3. J Exp Med. 1964 Jan 1;119:923–942. doi: 10.1084/jem.119.6.923. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. HUGGINS C., GRAND L., FUKUNISHI R. AROMATIC INFLUENCES ON THE YIELDS OF MAMMARY CANCERS FOLLOWING ADMINISTRATION OF 7,12-DIMETHYLBENZ(A)ANTHRACENE. Proc Natl Acad Sci U S A. 1964 May;51:737–742. doi: 10.1073/pnas.51.5.737. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. HUGGINS C., MORII S. Selective adrenal necrosis and apoplexy induced by 7, 12-dimethylbenz(a)anthracene. J Exp Med. 1961 Nov 1;114:741–760. doi: 10.1084/jem.114.5.741. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. RICHARDSON H. L., STIER A. R., BORSOS-NACHTNEBEL E. Liver tumor inhibition and adrenal histologic responses in rats to which 3'-methyl-4-dimethylaminoazobenzene and 20-methylcholanthrene were simultaneously administered. Cancer Res. 1952 May;12(5):356–361. [PubMed] [Google Scholar]

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