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. 1962 Dec;48(12):2094–2101. doi: 10.1073/pnas.48.12.2094

BASIS OF ACTINOMYCIN ACTION, I. DNA BINDING AND INHIBITION OF RNA-POLYMERASE SYNTHETIC REACTIONS BY ACTINOMYCIN

I H Goldberg 1,2,3,4, M Rabinowitz 1,2,3,4, E Reich 1,2,3,4
PMCID: PMC221129  PMID: 13948669

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. CHAMBERLIN M., BERG P. Deoxyribo ucleic acid-directed synthesis of ribonucleic acid by an enzyme from Escherichia coli. Proc Natl Acad Sci U S A. 1962 Jan 15;48:81–94. doi: 10.1073/pnas.48.1.81. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. FURTH J. J., HURWITZ J., GOLDMANN M. The directing role of DNA in RNA synthesis. Specificity of the deoxyadenylate deoxythymidvlate copolymer as a primer. Biochem Biophys Res Commun. 1961 Apr 28;4:431–435. doi: 10.1016/0006-291x(61)90303-5. [DOI] [PubMed] [Google Scholar]
  3. GOLDBERG I. H., RABINOWITZ M. Actionmycin D inhibition of deoxyribonucleic acid-dependent synthesis of ribonucleic acid. Science. 1962 Apr 27;136(3513):315–316. doi: 10.1126/science.136.3513.315. [DOI] [PubMed] [Google Scholar]
  4. GOLDBERG I. H., RABINOWITZ M. The enzymic synthesis of pseudouridine triphosphate. Biochim Biophys Acta. 1961 Nov 25;54:202–204. doi: 10.1016/0006-3002(61)90959-3. [DOI] [PubMed] [Google Scholar]
  5. HURWITZ J., FURTH J. J., MALAMY M., ALEXANDER M. The role of deoxyribonucleic acid in ribonucleic acid synthesis. III. The inhibition of the enzymatic synthesis of ribonucleic acid and deoxyribonucleic acid by actinomycin D and proflavin. Proc Natl Acad Sci U S A. 1962 Jul 15;48:1222–1230. doi: 10.1073/pnas.48.7.1222. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. JOSSE J., KAISER A. D., KORNBERG A. Enzymatic synthesis of deoxyribonucleic acid. VIII. Frequencies of nearest neighbor base sequences in deoxyribonucleic acid. J Biol Chem. 1961 Mar;236:864–875. [PubMed] [Google Scholar]
  7. KERSTEN W. Interaction of actinomycin C with constituents of nucleic acids. Biochim Biophys Acta. 1961 Mar 4;47:610–611. doi: 10.1016/0006-3002(61)90564-9. [DOI] [PubMed] [Google Scholar]
  8. KIRK J. M. The mode of action of actinomycin D. Biochim Biophys Acta. 1960 Jul 29;42:167–169. doi: 10.1016/0006-3002(60)90769-1. [DOI] [PubMed] [Google Scholar]
  9. LOWRY O. H., ROSEBROUGH N. J., FARR A. L., RANDALL R. J. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951 Nov;193(1):265–275. [PubMed] [Google Scholar]
  10. RAUEN H. M., KERSTEN H., KERSTEN W. [On the mode of action of actinomycins]. Hoppe Seylers Z Physiol Chem. 1960 Dec 2;321:139–147. doi: 10.1515/bchm2.1960.321.1.139. [DOI] [PubMed] [Google Scholar]
  11. REICH E., FRANKLIN R. M., SHATKIN A. J., TATUM E. L. Effect of actinomycin D on cellular nucleic acid synthesis and virus production. Science. 1961 Aug 25;134(3478):556–557. doi: 10.1126/science.134.3478.556. [DOI] [PubMed] [Google Scholar]
  12. REICH E., FRANKLIN R. M., SHATKIN A. J., TATUMEL Action of actinomycin D on animal cells and viruses. Proc Natl Acad Sci U S A. 1962 Jul 15;48:1238–1245. doi: 10.1073/pnas.48.7.1238. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. SCHACHMAN H. K., ADLER J., RADDING C. M., LEHMAN I. R., KORNBERG A. Enzymatic synthesis of deoxyribonucleic acid. VII. Synthesis of a polymer of deoxyadenylate and deoxythymidylate. J Biol Chem. 1960 Nov;235:3242–3249. [PubMed] [Google Scholar]
  14. SWARTZ M. N., TRAUTNER T. A., KORNBERG A. Enzymatic synthesis of deoxyribonucleic acid. XI. Further studies on nearest neighbor base sequences in deoxyribonucleic acids. J Biol Chem. 1962 Jun;237:1961–1967. [PubMed] [Google Scholar]
  15. TAMM C., HODES M. E., CHARGAFF E. The formation apurinic acid from the desoxyribonucleic acid of calf thymus. J Biol Chem. 1952 Mar;195(1):49–63. [PubMed] [Google Scholar]
  16. WEISS S. B. Biosynthesis of ribopolynucleotides. Fed Proc. 1962 Jan-Feb;21:120–126. [PubMed] [Google Scholar]

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