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. 1963 Oct;50(4):753–761. doi: 10.1073/pnas.50.4.753

RECONSTITUTION OF IMMUNOLOGIC ACTIVITY BY INTERACTION OF POLYPEPTIDE CHAINS OF ANTIBODIES*

G M Edelman 1, D E Olins 1, J A Gally 1, N D Zinder 1
PMCID: PMC221256  PMID: 14077507

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. EDELMAN G. M., BENACERRAF B., OVARY Z., POULIK M. D. Structural differences among antibodies of different specificities. Proc Natl Acad Sci U S A. 1961 Nov 15;47:1751–1758. doi: 10.1073/pnas.47.11.1751. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. EDELMAN G. M., BENACERRAF B., OVARY Z. STRUCTURE AND SPECIFICITY OF GUINEA PIG 7S ANTIBODIES. J Exp Med. 1963 Aug 1;118:229–244. doi: 10.1084/jem.118.2.229. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. EDELMAN G. M., BENACERRAF B. On structural and functional relations between antibodies and proteins of the gamma-system. Proc Natl Acad Sci U S A. 1962 Jun 15;48:1035–1042. doi: 10.1073/pnas.48.6.1035. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. EDELMAN G. M., GALLY J. A. The nature of Bence-Jones proteins. Chemical similarities to polypetide chains of myeloma globulins and normal gamma-globulins. J Exp Med. 1962 Aug 1;116:207–227. doi: 10.1084/jem.116.2.207. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. EDELMAN G. M., POULIK M. D. Studies on structural units of the gamma-globulins. J Exp Med. 1961 May 1;113:861–884. doi: 10.1084/jem.113.5.861. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. FARAH F. S., KERN M., EISEN H. N. The preparation and some properties of purified antibody specific for the 2,4-dinitrophenyl group. J Exp Med. 1960 Dec 1;112:1195–1210. doi: 10.1084/jem.112.6.1195. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. FLEISCHMAN J. B., PAIN R. H., PORTER R. R. Reduction of gamma-globulins. Arch Biochem Biophys. 1962 Sep;Suppl 1:174–180. [PubMed] [Google Scholar]
  8. FRANEK F., NEZLIN R. S. Recovery of antibody combining activity by interaction of different peptide chains isolated from purified horse antitoxins. Folia Microbiol (Praha) 1963 Mar;8:128–130. doi: 10.1007/BF02877236. [DOI] [PubMed] [Google Scholar]
  9. KUNKEL H. G. Zone electrophoresis. Methods Biochem Anal. 1954;1:141–170. doi: 10.1002/9780470110171.ch6. [DOI] [PubMed] [Google Scholar]
  10. LOEB T., ZINDER N. D. A bacteriophage containing RNA. Proc Natl Acad Sci U S A. 1961 Mar 15;47:282–289. doi: 10.1073/pnas.47.3.282. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. OLINS D. E., EDELMAN G. M. The antigenic structure of the polypeptide chains of human gamma-globulin. J Exp Med. 1962 Nov 1;116:635–651. doi: 10.1084/jem.116.5.635. [DOI] [PMC free article] [PubMed] [Google Scholar]

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