After publication of our recent article [1], we noticed an error in Table 6 'Relative risk for developing rheumatoid arthritis in patients, stratified for anti-cyclic citrullinated peptide (anti-CCP) antibodies'.
Under the heading of 'Anti-CCP antibody-positive', the first line should read 'HLA-shared epitope-negative', and the second line should read 'HLA-shared epitope-positive'. Similarly, under the heading 'Anti-CCP antibody-negative', the first line should read 'HLA-shared epitope-negative' and the second line should read 'HLA-shared epitope-positive'.
The correct table is given here as Table 1 (a corrected version of Table 6 [1]).
Table 1.
Relative risk for developing rheumatoid arthritis in patients, stratified for anti-cyclic citrullinated peptide (anti-CCP) antibodies
| Nonsmoking | Smoking | |||
| Cases/controls | Relative risk (95% confidence interval) | Cases/controls | Relative risk (confidence interval) | |
| Anti-CCP antibody-positive | ||||
| HLA-shared epitope-negative | 33/41 | 1.00 | 71/49 | 1.67 (0.95–2.94) |
| HLA-shared epitope-positive | 62/33 | 2.05 (1.12–3.75) | 143/21 | 7.61 (4.05–14.30) |
| Anti-CCP antibody-negative | ||||
| HLA-shared epitope-negative | 40/41 | 1.00 | 52/49 | 1.11 (0.63–1.95) |
| HLA-shared epitope-positive | 23/33 | 0.71 (0.37–1.38) | 31/21 | 1.92 (0.98–3.77) |
The combination of carriage of HLA-shared epitope alleles or not, and ever or never smoking were compared for groups stratified for anti-CCP antibodies.
See related research article by Kokkonen et al., http://arthritis-research.com/content/9/3/R56
References
- Kokkonen H, Johansson M, Innala L, Jidell E, Rantapää-Dahlqvist S. The PTPN22 1858C/T polymorphism is associated with anti-cyclic citrullinated peptide antibody-positive early rheumatoid arthritis in northern Sweden. Arthritis Res Ther. 2007;9:R56. doi: 10.1186/ar2214. [DOI] [PMC free article] [PubMed] [Google Scholar]
