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. 1982 Oct;152(1):49–56. doi: 10.1128/jb.152.1.49-56.1982

Regulatory region of the Klebsiella aerogenes tryptophan operon.

M Blumenberg, C Yanofsky
PMCID: PMC221373  PMID: 6181051

Abstract

The trp operon of Klebsiella aerogenes was cloned, and its regulatory region was sequenced. Comparison with previously reported trp regulatory sequences of other enteric bacteria indicates that the K. aerogenes trp promoter-operator region is most similar to the corresponding region of Salmonella typhimurium. The trp leader regions of K. aerogenes and other enteric bacteria are organized similarly, but there are significant differences in the stabilities of the predicted secondary structures in their leader transcripts. These differences should make the K. aerogenes attenuator a weaker transcription termination site than any of the other attenuator regions studied; this was confirmed in in vitro transcription experiments. The sequence of the leader transcript and the precise site of in vitro termination were determined.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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