Abstract
A strain of Neurospora crassa devoid of constitutive amino acid transport ability can utilize arginine as the sole nitrogen source. Nitrogen starvation, presence of arginine, and mutational inactivation of the general permease are key factors in signaling production of an extracellular enzyme which removes the alpha-amino group from the amino acid.
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Selected References
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- DeBusk B. G., DeBusk A. G. Molecular transport in Neurospora crassa. I. Biochemical properties of a phenylalanine permease. Biochim Biophys Acta. 1965 Jun 15;104(1):139–150. doi: 10.1016/0304-4165(65)90229-1. [DOI] [PubMed] [Google Scholar]
- DeBusk R. M., Brown D. T., DeBusk A. G., Penderghast R. D. Alternate mechanism for amino acid entry into Neurospora crassa: extracellular deamination and subsequent keto acid transport. J Bacteriol. 1981 Apr;146(1):163–169. doi: 10.1128/jb.146.1.163-169.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
- DeBusk R. M., DeBusk A. G. Physiological and regulatory properties of the general amino acid transport system of Neurospora crassa. J Bacteriol. 1980 Jul;143(1):188–197. doi: 10.1128/jb.143.1.188-197.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Foster K. W., Smyth R. D. Light Antennas in phototactic algae. Microbiol Rev. 1980 Dec;44(4):572–630. doi: 10.1128/mr.44.4.572-630.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Lester G. Genetic control of amino acid permeability in Neurospora crassa. J Bacteriol. 1966 Feb;91(2):677–684. doi: 10.1128/jb.91.2.677-684.1966. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Magill C. W., Nelson S. O., D'Ambrosio S. M., Glover G. I. Histidine uptake in mutant strains of Neurospora crassa via the general transport system for amino acids. J Bacteriol. 1973 Mar;113(3):1320–1325. doi: 10.1128/jb.113.3.1320-1325.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Marzluf G. A. Regulation of nitrogen metabolism and gene expression in fungi. Microbiol Rev. 1981 Sep;45(3):437–461. doi: 10.1128/mr.45.3.437-461.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ogilvie-Villa S., DeBusk R. M., DeBusk A. G. Characterization of 2-aminoisobutyric acid transport in Neurospora crassa: a general amino acid permease-specific substrate. J Bacteriol. 1981 Sep;147(3):944–948. doi: 10.1128/jb.147.3.944-948.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Pall M. L. Amino acid transport in Neurospora crassa. I. Properties of two amino acid transport systems. Biochim Biophys Acta. 1969 Jan 28;173(1):113–127. doi: 10.1016/0005-2736(69)90042-x. [DOI] [PubMed] [Google Scholar]
- Rao E. Y., Rao T. K., Debusk A. G. Isolation and characterization of a mutant of Neurospora crassa deficient in general amino acid permease activity. Biochim Biophys Acta. 1975 Nov 17;413(1):45–51. doi: 10.1016/0005-2736(75)90057-7. [DOI] [PubMed] [Google Scholar]
- Ray J., Lerner R. A. A biologically active receptor for the carbohydrate-binding protein(s) of Dictyostelium discoideum. Cell. 1982 Jan;28(1):91–98. doi: 10.1016/0092-8674(82)90378-6. [DOI] [PubMed] [Google Scholar]
- Stadler D. R. Genetic control of the uptake of amino acids in Neurospora. Genetics. 1966 Aug;54(2):677–685. doi: 10.1093/genetics/54.2.677. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Thwaites W. M., Pendyala L. Regulation of amino acid assimilation in a strain of Neurospora crassa lacking basic amino acid transport activity. Biochim Biophys Acta. 1969 Dec 30;192(3):455–461. doi: 10.1016/0304-4165(69)90394-8. [DOI] [PubMed] [Google Scholar]
- Wolfinbarger L., Jr, Jervis H. H., DeBusk A. G. Active transport of L-aspartic acid in Neurospora crassa. Biochim Biophys Acta. 1971 Oct 12;249(1):63–68. doi: 10.1016/0005-2736(71)90083-6. [DOI] [PubMed] [Google Scholar]