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. 1982 Nov;152(2):888–892. doi: 10.1128/jb.152.2.888-892.1982

Structural characteristics of tetanolysin and its binding to lipid vesicles.

S Rottem, R M Cole, W H Habig, M F Barile, M C Hardegree
PMCID: PMC221544  PMID: 7130132

Abstract

Tetanolysin binding to lipid vesicles was found to depend on the molar ratio of cholesterol to phospholipid, being low in vesicles containing up to 20 mol% cholesterol and high in vesicles containing more than 33 mol%. High concentrations of purified tetanolysin preparations formed arc- and ring-shaped structures. The structures were not readily detectable in diluted preparations unless incubated with lipid vesicles containing high molar ratios of cholesterol to phospholipid. It is suggested that the toxin is concentrated on the vesicles to local concentrations high enough to form the arcs and rings.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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