Abstract
The gene encoding nucleosidediphosphate kinase (ndk) was located at 55 units on the Salmonella typhimurium chromosome. The ndk locus was 83% cotransducible with hisS and 2% cotransducible with glyA in phage P22-mediated crosses. A nucleosidediphosphate kinase mutant that produced only 10% of the wild-type enzyme activity (ndk-1) grew normally and produced a heat-labile enzyme.
Full text
PDF


Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Beck C. F., Neuhard J., Thomassen E., Ingraham J. L., Kleker E. Salmonella typhimurium mutants defective in cytidine monophosphate kinase (cmk). J Bacteriol. 1974 Dec;120(3):1370–1379. doi: 10.1128/jb.120.3.1370-1379.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Garces E., Cleland W. W. Kinetic studies of yeast nucleoside diphosphate kinase. Biochemistry. 1969 Feb;8(2):633–640. doi: 10.1021/bi00830a026. [DOI] [PubMed] [Google Scholar]
- Ginther C. L., Ingraham J. L. Cold-sensitive mutant of Salmonella typhimurium defective in nucleosidediphosphokinase. J Bacteriol. 1974 Jun;118(3):1020–1026. doi: 10.1128/jb.118.3.1020-1026.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ginther C. L., Ingraham J. L. Nucleoside diphosphokinase of Salmonella typhimurium. J Biol Chem. 1974 Jun 10;249(11):3406–3411. [PubMed] [Google Scholar]
- Green L., Miller C. G. Genetic mapping of the Salmonella typhimurium pepB locus. J Bacteriol. 1980 Sep;143(3):1524–1526. doi: 10.1128/jb.143.3.1524-1526.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ingraham J. L., Neuhard J. Cold-sensitive mutants of Salmonella typhimurium defective in uridine monophosphate kinase (pyrH). J Biol Chem. 1972 Oct 10;247(19):6259–6265. [PubMed] [Google Scholar]
- Kleckner N., Chan R. K., Tye B. K., Botstein D. Mutagenesis by insertion of a drug-resistance element carrying an inverted repetition. J Mol Biol. 1975 Oct 5;97(4):561–575. doi: 10.1016/s0022-2836(75)80059-3. [DOI] [PubMed] [Google Scholar]
- Kleckner N., Roth J., Botstein D. Genetic engineering in vivo using translocatable drug-resistance elements. New methods in bacterial genetics. J Mol Biol. 1977 Oct 15;116(1):125–159. doi: 10.1016/0022-2836(77)90123-1. [DOI] [PubMed] [Google Scholar]
- Kleckner N., Steele D. A., Reichardt K., Botstein D. Specificity of insertion by the translocatable tetracycline-resistance element Tn10. Genetics. 1979 Aug;92(4):1023–1040. doi: 10.1093/genetics/92.4.1023. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Saeki T., Hori M., Umezawa H. Pyruvate kinase of Escherichia coli. Its role in supplying nucleoside triphosphates in cells under anaerobic conditions. J Biochem. 1974 Sep;76(3):631–637. doi: 10.1093/oxfordjournals.jbchem.a130607. [DOI] [PubMed] [Google Scholar]
- VOGEL H. J., BONNER D. M. Acetylornithinase of Escherichia coli: partial purification and some properties. J Biol Chem. 1956 Jan;218(1):97–106. [PubMed] [Google Scholar]
