Skip to main content
Journal of Bacteriology logoLink to Journal of Bacteriology
. 1977 Oct;132(1):346–348. doi: 10.1128/jb.132.1.346-348.1977

Induction of yeast killer factor mutations.

M Vodkin
PMCID: PMC221862  PMID: 334730

Abstract

Two related killer strains of Saccharomyces cerevisiae were mutagenized and screened for nonkiller variants. About 20% of the mutants derived from one strain lacked all detectable double-straned ribonucleic acid (dsRNA). About 70% of the mutants from the other strain lacked one of the dsRNA species normally associated with the killer factor and had in its place another species of dsRNA with a lower molecular weight.

Full text

PDF
346

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bevan E. A., Herring A. J., Mitchell D. J. Preliminary characterization of two species of dsRNA in yeast and their relationship to the "killer" character. Nature. 1973 Sep 14;245(5420):81–86. doi: 10.1038/245081b0. [DOI] [PubMed] [Google Scholar]
  2. Bevan E. A., Somers J. M. Somatic segregation of the killer (k) and neutral (n) cytoplasmic genetic determinants in yeast. Genet Res. 1969 Aug;14(1):71–77. doi: 10.1017/s0016672300001865. [DOI] [PubMed] [Google Scholar]
  3. Bussey H. Effects of yeast killer factor on sensitive cells. Nat New Biol. 1972 Jan 19;235(55):73–75. doi: 10.1038/newbio235073a0. [DOI] [PubMed] [Google Scholar]
  4. Fink G. R., Styles C. A. Curing of a killer factor in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 1972 Oct;69(10):2846–2849. doi: 10.1073/pnas.69.10.2846. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Herring A. J., Bevan E. A. Virus-like particles associated with the double-stranded RNA species found in killer and sensitive strains of the yeast Saccharomyces cerevisiae. J Gen Virol. 1974 Mar;22(3):387–394. doi: 10.1099/0022-1317-22-3-387. [DOI] [PubMed] [Google Scholar]
  6. Mitchell D. J., Herring A. J., Bevan E. A. The genetic control of DS-RNA virus-like particles associated with Saccharomyces cerevisiae killer yeast. Heredity (Edinb) 1976 Aug;37(1):129–134. doi: 10.1038/hdy.1976.71. [DOI] [PubMed] [Google Scholar]
  7. Nesterova G. F., Zekhnov A. M., Inge-Vechtomov S. G. Dominantnye nonsens-supressory, podavliaiushchie antagonisticheskuiu aktivnost' drozhzhei Saccharomyces cerevisiae. Genetika. 1975;11(8):96–103. [PubMed] [Google Scholar]
  8. Rasse-Messenguy F., Fink G. R. Temperature-sensitive nonsense suppressors in yeast. Genetics. 1973 Nov;75(3):459–464. doi: 10.1093/genetics/75.3.459. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Somers J. M., Bevan E. A. The inheritance of the killer character in yeast. Genet Res. 1969 Feb;13(1):71–83. doi: 10.1017/s0016672300002743. [DOI] [PubMed] [Google Scholar]
  10. Sweeney T. K., Tate A., Fink G. R. A study of the transmission and structure of double stranded RNAs associated with the killer phenomenon in Saccharomyces cerevisiae. Genetics. 1976 Sep;84(1):27–42. doi: 10.1093/genetics/84.1.27. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Vodkin M., Katterman F., Fink G. R. Yeast killer mutants with altered double-stranded ribonucleic acid. J Bacteriol. 1974 Feb;117(2):681–686. doi: 10.1128/jb.117.2.681-686.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Wickner R. B. Chromosomal and nonchromosomal mutations affecting the "killer character" of Saccharomyces cerevisiae. Genetics. 1974 Mar;76(3):423–432. doi: 10.1093/genetics/76.3.423. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Wickner R. B., Leibowitz M. J. Chromosomal genes essential for replication of a double-stranded RNA plasmid of Saccharomyces cerevisiae: the killer character of yeast. J Mol Biol. 1976 Aug 15;105(3):427–443. doi: 10.1016/0022-2836(76)90102-9. [DOI] [PubMed] [Google Scholar]
  14. Woods D. R., Bevan E. A. Studies on the nature of the killer factor produced by Saccharomyces cerevisiae. J Gen Microbiol. 1968 Apr;51(1):115–126. doi: 10.1099/00221287-51-1-115. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Bacteriology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES