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. 1977 Oct;132(1):352–355. doi: 10.1128/jb.132.1.352-355.1977

Effect of the relA gene on derepression of amino acid biosynthetic enzymes in growing Escherichia coli depends on the pathway being derepressed.

A V Furano, F P Wittel
PMCID: PMC221864  PMID: 334732

Abstract

Derepression of an enzyme in the arginine biosynthetic pathway, but not of an enzyme in the tryptophan biosynthetic pathway, is inhibited during the stringent response produced by a partial deprivation of valyl transfer ribonucleic acid in a rel+ strain. In contrast, derepression of the tryptophan biosynthetic enzyme, but not of the arginine biosynthetic enzyme, was inhibited during the relaxed response produced in an isogenic relA strain by the partial deprivation of valyl transfer ribonucleic acid.

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Selected References

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