Abstract
A wide spectrum of liver disease is seen in general practice. For the most part, asymptomatic increases in transaminase may be followed for several months, but the treatable conditions described should be ruled out early on. It is essential do diagnose as promptly as possible Wilson's disease, hemochromatosis, autoimmune heaptitis, and hepatitis B. Drugs are a frequent cause of wild transaminitis. Heavy alcohol consumption as a cause of liver disease must always be suspected, but may be difficult to prove.
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Selected References
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- Hoofnagle J. H., Mullen K. D., Jones D. B., Rustgi V., Di Bisceglie A., Peters M., Waggoner J. G., Park Y., Jones E. A. Treatment of chronic non-A,non-B hepatitis with recombinant human alpha interferon. A preliminary report. N Engl J Med. 1986 Dec 18;315(25):1575–1578. doi: 10.1056/NEJM198612183152503. [DOI] [PubMed] [Google Scholar]
- Hultcrantz R., Glaumann H., Lindberg G., Nilsson L. H. Liver investigation in 149 asymptomatic patients with moderately elevated activities of serum aminotransferases. Scand J Gastroenterol. 1986 Jan;21(1):109–113. doi: 10.3109/00365528609034632. [DOI] [PubMed] [Google Scholar]
- Orrego H., Blake J. E., Blendis L. M., Compton K. V., Israel Y. Long-term treatment of alcoholic liver disease with propylthiouracil. N Engl J Med. 1987 Dec 3;317(23):1421–1427. doi: 10.1056/NEJM198712033172301. [DOI] [PubMed] [Google Scholar]
- Thomas H. C., Scully L. J. Antiviral therapy in hepatitis B infection. Br Med Bull. 1985 Oct;41(4):374–380. doi: 10.1093/oxfordjournals.bmb.a072079. [DOI] [PubMed] [Google Scholar]