Abstract
Aggregative amoebae of Dictyostelium minutum are not attracted by cyclic AMP; they are sensitive to various attracting sources from which yeast extract was chosen to purify the chemoattractant. A small acrasin-like species-specific molecule which contains glycine and C5H5N5 has been purified 30,000-fold. Several characteristics of this chemotactic molecule, which is inactivated by an enzyme that is not species specific, are described.
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Selected References
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- Konijn T. M. Microbiological assay of cyclic 3',5'-AMP. Experientia. 1970 Apr 15;26(4):367–369. doi: 10.1007/BF01896891. [DOI] [PubMed] [Google Scholar]
- Mato J. M., van Haastert P. J., Krens F. A., Konijn T. M. An acrasin-like attractant from yeast extract specific for Dictyostelium lacteum. Dev Biol. 1977 Jun;57(2):450–453. doi: 10.1016/0012-1606(77)90229-9. [DOI] [PubMed] [Google Scholar]
- Pan P., Hall E. M., Bonner J. T. Determination of the active portion of the folic acid molecule in cellular slime mold chemotaxis. J Bacteriol. 1975 Apr;122(1):185–191. doi: 10.1128/jb.122.1.185-191.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Wurster B., Pan P., Tyan G. G., Bonner J. T. Preliminary characterization of the acrasin of the cellular slime mold Polysphondylium violaceum. Proc Natl Acad Sci U S A. 1976 Mar;73(3):795–799. doi: 10.1073/pnas.73.3.795. [DOI] [PMC free article] [PubMed] [Google Scholar]