Abstract
X-ray diffraction photographs of a nucleoprotein preparation from Escherichia coli show the A-type pattern of crystalline deoxyribonucleic acid (DNA). This suggests that a large part of the DNA is free from protein. In higher organisms DNA does not exist in this form but is closely bound to protein.
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Selected References
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- FEUGHELMAN M., LANGRIDGE R., SEEDS W. E., STOKES A. R., WILSON H. R., HOOPER C. W., WILKINS M. H., BARCLAY R. K., HAMILTON L. D. Molecular structure of deoxyribose nucleic acid and nucleoprotein. Nature. 1955 May 14;175(4463):834–838. [PubMed] [Google Scholar]
- KIRBY K. S. Preparation of some deoxyribonucleic acid-protein complexes from rat-liver homogenates. Biochem J. 1958 Oct;70(2):260–265. doi: 10.1042/bj0700260. [DOI] [PMC free article] [PubMed] [Google Scholar]
- WILKINS M. H. Physical studies of the molecular structure of deoxyribose nucleic acid and nucleoprotein. Cold Spring Harb Symp Quant Biol. 1956;21:75–90. doi: 10.1101/sqb.1956.021.01.007. [DOI] [PubMed] [Google Scholar]
- WILKINS M. H., SEEDS W. E., STOKES A. R., WILSON H. R. Helical structure of crystalline deoxypentose nucleic acid. Nature. 1953 Oct 24;172(4382):759–762. doi: 10.1038/172759b0. [DOI] [PubMed] [Google Scholar]