Abstract
The stoichiometry of cyclic AMP binding protein to cyclic AMP in sporulating cells of Blastocladiella emersonii and the resistance of protein-bound cyclic AMP to enzyme-catalyzed hydrolysis suggest that the distribution of cyclic AMP between free and protein-bound pools is an important factor in cyclic AMP metabolism. Most but not all of the cyclic AMP binding protein in sporulating cells is associated with a cyclic AMP-dependent protein kinase.
Full text
PDFSelected References
These references are in PubMed. This may not be the complete list of references from this article.
- Beavo J. A., Bechtel P. J., Krebs E. G. Mechanisms of control for cAMP-dependent protein kinase from skeletal muscle. Adv Cyclic Nucleotide Res. 1975;5:241–251. [PubMed] [Google Scholar]
- Brostrom C. O., Corbin J. D., King C. A., Krebs E. G. Interaction of the subunits of adenosine 3':5'-cyclic monophosphate-dependent protein kinase of muscle. Proc Natl Acad Sci U S A. 1971 Oct;68(10):2444–2447. doi: 10.1073/pnas.68.10.2444. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Epstein P. M., Silverman P. M. Induction of cyclic AMP phosphodiesterase in Blastocladiella emersonii and its relation to cyclic AMP metabolism. J Bacteriol. 1978 Sep;135(3):968–975. doi: 10.1128/jb.135.3.968-975.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gilman A. G. A protein binding assay for adenosine 3':5'-cyclic monophosphate. Proc Natl Acad Sci U S A. 1970 Sep;67(1):305–312. doi: 10.1073/pnas.67.1.305. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hofmann F., Bechtel P. J., Krebs E. G. Concentrations of cyclic AMP-dependent protein kinase subunits in various tissues. J Biol Chem. 1977 Feb 25;252(4):1441–1447. [PubMed] [Google Scholar]
- Khac L. D., Harbon S., Clauser H. J. Intracellular titration of cyclic AMP bound to receptor proteins and correlation with cyclic-AMP levels in the surviving rat diaphragm. Eur J Biochem. 1973 Dec 3;40(1):177–185. doi: 10.1111/j.1432-1033.1973.tb03183.x. [DOI] [PubMed] [Google Scholar]
- Krebs E. G. Protein kinases. Curr Top Cell Regul. 1972;5:99–133. [PubMed] [Google Scholar]
- Murphy M. N., Lovett J. S. RNA and protein synthesis during zoospore differentiation in synchronized cultures of Blastocladiella. Dev Biol. 1966 Aug;14(1):68–95. doi: 10.1016/0012-1606(66)90006-6. [DOI] [PubMed] [Google Scholar]
- O'Dea R. F., Haddox M. K., Goldberg N. D. Interaction with phosphodiesterase of free and kinase-complexed cyclic adenosine 3',5'-monophosphate. J Biol Chem. 1971 Oct 25;246(20):6183–6190. [PubMed] [Google Scholar]
- Rubin C. S., Erlichman J., Rosen O. M. Cyclic AMP-dependent protein kinase from bovine heart muscle. Methods Enzymol. 1974;38:308–315. doi: 10.1016/0076-6879(74)38047-0. [DOI] [PubMed] [Google Scholar]
- Sy J., Richter D. Separation of a cyclic 3',5'-adenosine monophosphate binding protein from yeast. Biochemistry. 1972 Jul 18;11(15):2784–2787. doi: 10.1021/bi00765a008. [DOI] [PubMed] [Google Scholar]
- Takai Y., Yamamura H., Nishizuka Y. Adenosine 3':5'-monophosphate-dependent protein kinase from yeast. J Biol Chem. 1974 Jan 25;249(2):530–535. [PubMed] [Google Scholar]
- Terasaki W. L., Brooker G. Cardiac adenosine 3':5'-monophosphate. Free and bound forms in the isolated rat atrium. J Biol Chem. 1977 Feb 10;252(3):1041–1050. [PubMed] [Google Scholar]