TABLE 2. Fold Change in Selected Genes, Sickle Cell Disease Versus Control Subjects.

	Fold Change
Gene Name	MA	QPCR	P
Arg2	3.29	2.83	<0.006
ODC	1.33	1.31	<0.005
OAT	–1.08	–1.21	NS
CAT-2	1.22	1.44	<0.01
eNOS	–1.51	–1.03	NS
iNOS	1.1	1.08	NS
AL	–1.02	–1.39	NS
ASS	1.33	1.78	<0.05
SS	1.92	1.56	<0.05
SRM	1.61	1.26	<0.05
P5CR	2.09	1.65	<0.005

MA indicates microarray; QPCR, quantitative polymerase chain reaction; Arg 2, arginase 2; ODC, ornithine decarboxylase; OAT, ornithine aminotransferase; CAT-2, cationic amino acid transporter-2; eNOS, endothelial NO synthase; iNOS, inducible NO synthase; AL, argininosuccinate lyase; ASS, argininosuccinate synthetase; SS, spermine synthase; SRM, spermidine synthase; and P5CR, pyrroline-5-carboxylate reductase.