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. 1959 Jul;45(7):1016–1026. doi: 10.1073/pnas.45.7.1016

THE EFFECTS OF DELETIONS, POINT MUTATIONS, REVERSIONS AND SUPPRESSOR MUTATIONS ON THE TWO COMPONENTS OF THE TRYPTOPHAN SYNTHETASE OF ESCHERICHIA COLI*

Charles Yanofsky 1, Irving P Crawford 1,
PMCID: PMC222680  PMID: 16590470

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Benzer S., Freese E. INDUCTION OF SPECIFIC MUTATIONS WITH 5-BROMOURACIL. Proc Natl Acad Sci U S A. 1958 Feb;44(2):112–119. doi: 10.1073/pnas.44.2.112. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. CATCHESIDE D. G., OVERTON A. Complementation between alleles in heterocaryons. Cold Spring Harb Symp Quant Biol. 1958;23:137–140. doi: 10.1101/sqb.1958.023.01.017. [DOI] [PubMed] [Google Scholar]
  3. Crawford I. P., Yanofsky C. ON THE SEPARATION OF THE TRYPTOPHAN SYNTHETASE OF ESCHERICHIA COLI INTO TWO PROTEIN COMPONENTS. Proc Natl Acad Sci U S A. 1958 Dec 15;44(12):1161–1170. doi: 10.1073/pnas.44.12.1161. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. HUNT J. A., INGRAM V. M. Allelomorphism and the chemical differences of the human haemoglobins A, S and C. Nature. 1958 Apr 12;181(4615):1062–1063. doi: 10.1038/1811062a0. [DOI] [PubMed] [Google Scholar]
  5. INGRAM V. M. Gene mutations in human haemoglobin: the chemical difference between normal and sickle cell haemoglobin. Nature. 1957 Aug 17;180(4581):326–328. doi: 10.1038/180326a0. [DOI] [PubMed] [Google Scholar]
  6. LERNER P., YANOFSKY C. An immunological study of mutants of Escherichia coli lacking the enzyme tryptophan synthetase. J Bacteriol. 1957 Oct;74(4):494–501. doi: 10.1128/jb.74.4.494-501.1957. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. LOWRY O. H., ROSEBROUGH N. J., FARR A. L., RANDALL R. J. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951 Nov;193(1):265–275. [PubMed] [Google Scholar]
  8. PARDEE A. B., JACOB F., MONOD J. Sur l'expression et le rôle des allèles inductible et constitutif dans la synthèse de la beta-galactosidase chez des zygotes d'Escherichia coli. C R Hebd Seances Acad Sci. 1958 May 28;246(21):3125–3128. [PubMed] [Google Scholar]
  9. SUSKIND S. R. Properties of a protein antigenically related to tryptophan synthetase in Neurospora crassa. J Bacteriol. 1957 Sep;74(3):308–318. doi: 10.1128/jb.74.3.308-318.1957. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Singer S. J., Itano H. A. ON THE ASYMMETRICAL DISSOCIATION OF HUMAN HEMOGLOBIN. Proc Natl Acad Sci U S A. 1959 Feb;45(2):174–184. doi: 10.1073/pnas.45.2.174. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Suskind S. R., Yanofsky C., Bonner D. M. ALLELIC STRAINS OF Neurospora LACKING TRYPTOPHAN SYNTHETASE: A PRELIMINARY IMMUNOCHEMICAL CHARACTERIZATION. Proc Natl Acad Sci U S A. 1955 Aug 15;41(8):577–582. doi: 10.1073/pnas.41.8.577. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Woodward D. O., Partridge C. W., Giles N. H. COMPLEMENTATION AT THE AD-4 LOCUS IN NEUROSPORA CRASSA. Proc Natl Acad Sci U S A. 1958 Dec 15;44(12):1237–1244. doi: 10.1073/pnas.44.12.1237. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. YANOFSKY C. A second reaction catalyzed by the tryptophan synthetase of Escherichia coli. Biochim Biophys Acta. 1959 Feb;31(2):408–416. doi: 10.1016/0006-3002(59)90015-0. [DOI] [PubMed] [Google Scholar]
  14. YANOFSKY C., RACHMELER M. The exclusion of free indole as an intermediate in the biosynthesis of tryptophan in Neurospora crassa. Biochim Biophys Acta. 1958 Jun;28(3):640–641. doi: 10.1016/0006-3002(58)90533-x. [DOI] [PubMed] [Google Scholar]
  15. YANOFSKY C. The absence of a tryptophan-niacin relationship in Escherichia coli and Bacillus subtilis. J Bacteriol. 1954 Nov;68(5):577–584. doi: 10.1128/jb.68.5.577-584.1954. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Yanofsky C., Stadler J. THE ENZYMATIC ACTIVITY ASSOCIATED WITH THE PROTEIN IMMUNOLOGICALLY RELATED TO TRYPTOPHAN SYNTHETASE. Proc Natl Acad Sci U S A. 1958 Mar;44(3):245–253. doi: 10.1073/pnas.44.3.245. [DOI] [PMC free article] [PubMed] [Google Scholar]

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