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. 1960 Feb;46(2):178–186. doi: 10.1073/pnas.46.2.178

BIOCHEMICAL AND NUTRITIONAL STUDIES ON THE INDUCTION OF FATTY LIVERS BY DIETARY OROTIC ACID^{^*}

R E Handschumacher ^1,^2,^†, W A Creasey ^1,^2,^‡, J J Jaffe ^1,², C A Pasternak ^1,^2,^‡,^§, L Hankin ^1,²

PMCID: PMC222812 PMID: 16590605

178

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

BEST C. H., HARTROFT W. S., SELLERS E. A. The protection of the liver by dietary factors. Gastroenterology. 1952 Mar;20(3):375–384. [PubMed] [Google Scholar]
CARROLL N. V., LONGLEY R. W., ROE J. H. The determination of glycogen in liver and muscle by use of anthrone reagent. J Biol Chem. 1956 Jun;220(2):583–593. [PubMed] [Google Scholar]
HALLANGER L. E., LAAKSO J. W., SCHULTZE M. O. Orotic acid in milk. J Biol Chem. 1953 May;202(1):83–89. [PubMed] [Google Scholar]
HANDSCHUMACHER R. E., PASTERNAK C. A. Inhibition of orotidylic acid decarboxylase, a primary site of carcinostasis by 6-azauracil. Biochim Biophys Acta. 1958 Nov;30(2):451–452. doi: 10.1016/0006-3002(58)90088-x. [DOI] [PubMed] [Google Scholar]
KREBS H. A. Body size and tissue respiration. Biochim Biophys Acta. 1950 Jan;4(1-3):249–269. doi: 10.1016/0006-3002(50)90032-1. [DOI] [PubMed] [Google Scholar]
PHILIPS F. S., THIERSCH J. B., BENDICH A. Adenine intoxication in relation to in vivo formation and deposition of 2,8-dioxyadenine in renal tubules. J Pharmacol Exp Ther. 1952 Jan;104(1):20–30. [PubMed] [Google Scholar]
STANDERFER S. B., HANDLER P. Fatty liver induced by orotic acid feeding. Proc Soc Exp Biol Med. 1955 Oct;90(1):270–271. doi: 10.3181/00379727-90-22005. [DOI] [PubMed] [Google Scholar]
STONE J. E., POTTER V. R. Biochemical screening of pyrimidine antimetabolites. II. The development of a system with a non-oxidative energy source. Cancer Res. 1957 Sep;17(8):794–799. [PubMed] [Google Scholar]

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