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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1969 Dec;64(4):1300–1307. doi: 10.1073/pnas.64.4.1300

Escherichia coli MUTANTS DEFECTIVE IN CHEMOTAXIS TOWARD SPECIFIC CHEMICALS*

Gerald L Hazelbauer 1,2, Robert E Mesibov 1,2, Julius Adler 1,2
PMCID: PMC223283  PMID: 4916925

Abstract

Mutants of Escherichia coli K12 have been found which fail to carry out chemotaxis toward certain chemicals only. One mutant exhibits greatly reduced chemotaxis toward L-serine but has no detectable defect either in uptake or in oxidative metabolism of that compound. Another mutant is not attracted to D-galactose and certain related sugars. There is a correlation between the galactose chemotaxis defect and a defect in galactose uptake, perhaps indicating a common component for chemotaxis and uptake systems. The results are discussed in terms of a model for chemotaxis in which attractants are detected by specific “chemoreceptors.”

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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