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Proceedings of the AMIA Annual Fall Symposium logoLink to Proceedings of the AMIA Annual Fall Symposium
. 1997:829–833.

Identification of findings suspicious for breast cancer based on natural language processing of mammogram reports.

N L Jain 1, C Friedman 1
PMCID: PMC2233320  PMID: 9357741

Abstract

There is need for encoded data for computerized clinical decision support, but most such data are unavailable as they are in free-text reports. Natural language processing offers one alternative for encoding such data. MedLEE is a natural language processing system which is in routine use for encoding chest radiograph and mammogram reports. In this paper, we study MedLEE's ability to identify mammogram findings suspicious for breast cancer by comparing MedLEE's encoding with a logbook of all suspicious findings maintained by the mammography center. While MedLEE was able to identify all the suspicious findings, it varied in the level of granularity, particularly about the location of the suspicious finding. Thus, natural language processing is a useful technique for encoding mammogram reports in order to detect suspicious findings.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bell D. S., Pattison-Gordon E., Greenes R. A. Experiments in concept modeling for radiographic image reports. J Am Med Inform Assoc. 1994 May-Jun;1(3):249–262. doi: 10.1136/jamia.1994.95236156. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Classen D. C., Pestotnik S. L., Evans R. S., Burke J. P. Computerized surveillance of adverse drug events in hospital patients. JAMA. 1991 Nov 27;266(20):2847–2851. [PubMed] [Google Scholar]
  3. Friedman C., Alderson P. O., Austin J. H., Cimino J. J., Johnson S. B. A general natural-language text processor for clinical radiology. J Am Med Inform Assoc. 1994 Mar-Apr;1(2):161–174. doi: 10.1136/jamia.1994.95236146. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Haug P. J., Koehler S., Lau L. M., Wang P., Rocha R., Huff S. M. Experience with a mixed semantic/syntactic parser. Proc Annu Symp Comput Appl Med Care. 1995:284–288. [PMC free article] [PubMed] [Google Scholar]
  5. Hripcsak G., Clayton P. D., Jenders R. A., Cimino J. J., Johnson S. B. Design of a clinical event monitor. Comput Biomed Res. 1996 Jun;29(3):194–221. doi: 10.1006/cbmr.1996.0016. [DOI] [PubMed] [Google Scholar]
  6. Hripcsak G., Friedman C., Alderson P. O., DuMouchel W., Johnson S. B., Clayton P. D. Unlocking clinical data from narrative reports: a study of natural language processing. Ann Intern Med. 1995 May 1;122(9):681–688. doi: 10.7326/0003-4819-122-9-199505010-00007. [DOI] [PubMed] [Google Scholar]
  7. Hripcsak G., Ludemann P., Pryor T. A., Wigertz O. B., Clayton P. D. Rationale for the Arden Syntax. Comput Biomed Res. 1994 Aug;27(4):291–324. doi: 10.1006/cbmr.1994.1023. [DOI] [PubMed] [Google Scholar]
  8. Jain N. L., Knirsch C. A., Friedman C., Hripcsak G. Identification of suspected tuberculosis patients based on natural language processing of chest radiograph reports. Proc AMIA Annu Fall Symp. 1996:542–546. [PMC free article] [PubMed] [Google Scholar]
  9. Kelsey J. L., Bernstein L. Epidemiology and prevention of breast cancer. Annu Rev Public Health. 1996;17:47–67. doi: 10.1146/annurev.pu.17.050196.000403. [DOI] [PubMed] [Google Scholar]
  10. Kuhn K., Zemmler T., Reichert M., Rösner D., Baumiller O., Knapp H. An integrated knowledge-based system to guide the physician during structured reporting. Methods Inf Med. 1994 Oct;33(4):417–422. [PubMed] [Google Scholar]
  11. Moorman P. W., van Ginneken A. M., van der Lei J., van Bemmel J. H. A model for structured data entry based on explicit descriptional knowledge. Methods Inf Med. 1994 Dec;33(5):454–463. [PubMed] [Google Scholar]
  12. Overhage J. M., Tierney W. M., McDonald C. J. Computer reminders to implement preventive care guidelines for hospitalized patients. Arch Intern Med. 1996 Jul 22;156(14):1551–1556. [PubMed] [Google Scholar]
  13. Sager N., Lyman M., Bucknall C., Nhan N., Tick L. J. Natural language processing and the representation of clinical data. J Am Med Inform Assoc. 1994 Mar-Apr;1(2):142–160. doi: 10.1136/jamia.1994.95236145. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Smart C. R., Hendrick R. E., Rutledge J. H., 3rd, Smith R. A. Benefit of mammography screening in women ages 40 to 49 years. Current evidence from randomized controlled trials. Cancer. 1995 Apr 1;75(7):1619–1626. doi: 10.1002/1097-0142(19950401)75:7<1619::aid-cncr2820750711>3.0.co;2-t. [DOI] [PubMed] [Google Scholar]
  15. Smigel K. NCI proposes new breast cancer screening guidelines. J Natl Cancer Inst. 1993 Oct 20;85(20):1626–1628. doi: 10.1093/jnci/85.20.1626. [DOI] [PubMed] [Google Scholar]
  16. Tierney W. M., McDonald C. J., Hui S. L., Martin D. K. Computer predictions of abnormal test results. Effects on outpatient testing. JAMA. 1988 Feb 26;259(8):1194–1198. [PubMed] [Google Scholar]
  17. Tierney W. M., McDonald C. J., Martin D. K., Rogers M. P. Computerized display of past test results. Effect on outpatient testing. Ann Intern Med. 1987 Oct;107(4):569–574. doi: 10.7326/0003-4819-107-4-569. [DOI] [PubMed] [Google Scholar]
  18. Tierney W. M., Miller M. E., McDonald C. J. The effect on test ordering of informing physicians of the charges for outpatient diagnostic tests. N Engl J Med. 1990 May 24;322(21):1499–1504. doi: 10.1056/NEJM199005243222105. [DOI] [PubMed] [Google Scholar]
  19. Tierney W. M., Miller M. E., Overhage J. M., McDonald C. J. Physician inpatient order writing on microcomputer workstations. Effects on resource utilization. JAMA. 1993 Jan 20;269(3):379–383. [PubMed] [Google Scholar]
  20. Zingmond D., Lenert L. A. Monitoring free-text data using medical language processing. Comput Biomed Res. 1993 Oct;26(5):467–481. doi: 10.1006/cbmr.1993.1033. [DOI] [PubMed] [Google Scholar]
  21. do Amaral M. B., Satomura Y. Structuring medical information into a language-independent database. Med Inform (Lond) 1994 Jul-Sep;19(3):269–282. doi: 10.3109/14639239409025332. [DOI] [PubMed] [Google Scholar]

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