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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1969 Oct;64(2):573–577. doi: 10.1073/pnas.64.2.573

A MECHANISM FOR GENETIC RECOMBINATION GENERATING ONE PARENT AND ONE RECOMBINANT*

Thierry Boon 1, Norton D Zinder 1
PMCID: PMC223382  PMID: 5261034

Abstract

A mechanism is proposed for generating one parental and one recombinant genome in a single recombination event between two DNA molecules. Three stages of the event are described: initiation, replication, and return. Initiation requires breakage and joining of strands. Replication proceeds through a biparental “replication fork” generated in initiation. Return also involves breakage and joining of strands. Some of the implications of such a mechanism for genetic recombination are discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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