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. 1969 Aug;63(4):1370–1376. doi: 10.1073/pnas.63.4.1370

In vitro SYNTHESIS OF DIFFERENT CATEGORIES OF SPECIFIC PROTEIN BY MEMBRANE-BOUND AND FREE RIBOSOMES*

M Clelia Ganoza 1,†, Curtis A Williams 1
PMCID: PMC223474  PMID: 5260940

Abstract

The free and membrane-bound ribosomes of hepatic cells were isolated and used to program protein synthesis in cell-free extracts. Immuno-electrophoretic and radioautographic analysis of the products showed that the membrane-bound ribosomes synthesized serum proteins, whereas ribosomes free of endoplasmic reticulum synthesized specific nonserum liver proteins. After synthesis, the serum proteins remained associated with membrane vesicles, whereas the other liver proteins were found free of cytoplasmic organelles.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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