Skip to main content
Epidemiology and Infection logoLink to Epidemiology and Infection
. 1987 Apr;98(2):191–197. doi: 10.1017/s0950268800061902

Experimental infection of monkeys with Leptospira interrogans serovar hardjo.

M F Palmer, S A Waitkins, R B Fitzgeorge, A Baskerville
PMCID: PMC2235241  PMID: 3549342

Abstract

Grivet monkeys experimentally infected with two different strains of Leptospira interrogans serovar hardjo showed no signs of severe clinical disease. There were no significant macroscopic lesions in any of the tissues examined, but the organisms were demonstrated in various tissues by immunofluorescent technique and were isolated from the blood and urine of two monkeys and the kidney of one. Abraded skin was shown to be a viable route of infection in non-human primates.

Full text

PDF
191

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ellinghausen H. C., Jr Growth temperatures, virulence, survival, and nutrition of leptospires. J Med Microbiol. 1973 Nov;6(4):487–497. doi: 10.1099/00222615-6-4-487. [DOI] [PubMed] [Google Scholar]
  2. Ellis W. A., Michna S. W. Bovine leptospirosis: demonstration of leptospires of the Hebdomadis serogroup in aborted fetuses and a premature calf. Vet Rec. 1976 Nov 27;99(22):430–432. doi: 10.1136/vr.99.22.430. [DOI] [PubMed] [Google Scholar]
  3. Ellis W. A., O'Brien J. J., Cassells J. Role of cattle in the maintenance of Leptospira interrogans serotype hardjo infection in Northern Ireland. Vet Rec. 1981 Jun 27;108(26):555–557. doi: 10.1136/vr.108.26.555. [DOI] [PubMed] [Google Scholar]
  4. Ellis W. A., O'Brien J. J., Neill S. D., Ferguson H. W., Hanna J. Bovine leptospirosis: microbiological and serological findings in aborted fetuses. Vet Rec. 1982 Feb 13;110(7):147–150. doi: 10.1136/vr.110.7.147. [DOI] [PubMed] [Google Scholar]
  5. Ellis W. A., O'Brien J. J., Neill S., Hanna J., Bryson D. G. The isolation of a leptospire from an aborted bovine fetus. Vet Rec. 1976 Dec 4;99(23):458–459. doi: 10.1136/vr.99.23.458. [DOI] [PubMed] [Google Scholar]
  6. Ellis W. A., O'Brien J. J., Pearson J. K., Collins D. S. Bovine leptospirosis: infection by the Hebdomadis serogroup and mastitis. Vet Rec. 1976 Nov 6;99(19):368–370. doi: 10.1136/vr.99.19.368. [DOI] [PubMed] [Google Scholar]
  7. Johnson R. C., Harris V. G. Differentiation of pathogenic and saprophytic letospires. I. Growth at low temperatures. J Bacteriol. 1967 Jul;94(1):27–31. doi: 10.1128/jb.94.1.27-31.1967. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Marshall R. B., BAskerville A., Hambleton P., Adams G. D. Benign leptospirosis: the pathology of experimental infection of monkeys with Leptospira interrogans serovars balcanica and tarassovi. Br J Exp Pathol. 1980 Apr;61(2):124–131. [PMC free article] [PubMed] [Google Scholar]
  9. Turner L. H. Leptospirosis. II. Serology. Trans R Soc Trop Med Hyg. 1968;62(6):880–899. doi: 10.1016/0035-9203(68)90017-5. [DOI] [PubMed] [Google Scholar]
  10. Waitkins S. A. From the PHLS. Update on leptospirosis. Br Med J (Clin Res Ed) 1985 May 18;290(6480):1502–1503. doi: 10.1136/bmj.290.6480.1502. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Woods S. B., Maley A. D., Frerichs G. N., Bailey J. Isolation of a hamster lethal strain of Leptospira interrogans serotype hardjo. Vet Rec. 1983 Apr 30;112(18):437–438. doi: 10.1136/vr.112.18.437. [DOI] [PubMed] [Google Scholar]

Articles from Epidemiology and Infection are provided here courtesy of Cambridge University Press

RESOURCES