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. 1969 Jun;63(2):532–539. doi: 10.1073/pnas.63.2.532

“TRANSCRIPTIONAL MAPPING,” I. INTRODUCTION TO THE METHOD AND THE USE OF ACTINOMYCIN D AS A TRANSCRIPTIONAL MAPPING AGENT

Michael Bleyman 1, Carl Woese 1
PMCID: PMC223596  PMID: 4979328

Abstract

The transcription process can in theory be used for genetic mapping on the “intraoperonal” level. We have shown that such an approach, utilizing actinomycin D to create blocks to the travel of the transcription enzyme, is indeed feasible, and the effects of actinomycin D on the synthesis of general pulse-labeled RNA are reported herein.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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