Abstract
Chronic cough of unknown etiology is often difficult to diagnose, thus, there exists controversy regarding the management of such patients. Although the ACCP (American College of Chest Physicians) statement in 1998 recommended that treatment should follow testing, recent evidence suggests that empirical treatment of GERD is more cost-effective than testing followed by treatment, in both chronic cough and non-cardiac chest pain. In this paper, we evaluated the cost-effectiveness in managing patients with chronic unexplained cough by building a decision model, and compared the cost-effectiveness of six most common management strategies. The outcome of our analysis demonstrates that empirical treatment is the cheapest option, while testing followed by treatment is the most expensive option with the shortest time course.
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- Borzecki A. M., Pedrosa M. C., Prashker M. J. Should noncardiac chest pain be treated empirically? A cost-effectiveness analysis. Arch Intern Med. 2000 Mar 27;160(6):844–852. doi: 10.1001/archinte.160.6.844. [DOI] [PubMed] [Google Scholar]
- Ing A. J., Ngu M. C. Cough and gastro-oesophageal reflux. Lancet. 1999 Mar 20;353(9157):944–946. doi: 10.1016/S0140-6736(98)00354-7. [DOI] [PubMed] [Google Scholar]
- Irwin R. S., Curley F. J., French C. L. Chronic cough. The spectrum and frequency of causes, key components of the diagnostic evaluation, and outcome of specific therapy. Am Rev Respir Dis. 1990 Mar;141(3):640–647. doi: 10.1164/ajrccm/141.3.640. [DOI] [PubMed] [Google Scholar]
- Irwin R. S., Madison J. M. The diagnosis and treatment of cough. N Engl J Med. 2000 Dec 7;343(23):1715–1721. doi: 10.1056/NEJM200012073432308. [DOI] [PubMed] [Google Scholar]