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. 1967 May;57(5):1345–1349. doi: 10.1073/pnas.57.5.1345

The paucity of species-specific amino acid residues in the variable regions of human and mouse Bence-Jones proteins and its evolutionary and genetic implications.

E A Kabat
PMCID: PMC224478  PMID: 5231739

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Doolittle R. F. The amino-terminal amino acid sequences of rabbit immunoglobulin light chains. Proc Natl Acad Sci U S A. 1966 May;55(5):1195–1201. doi: 10.1073/pnas.55.5.1195. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Dreyer W. J., Bennett J. C. The molecular basis of antibody formation: a paradox. Proc Natl Acad Sci U S A. 1965 Sep;54(3):864–869. doi: 10.1073/pnas.54.3.864. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. EDELMAN G. M., GALLY J. A. The nature of Bence-Jones proteins. Chemical similarities to polypetide chains of myeloma globulins and normal gamma-globulins. J Exp Med. 1962 Aug 1;116:207–227. doi: 10.1084/jem.116.2.207. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Goodman J. W., Donch J. J. Phage-neutralizing activity in light polypeptide chains of rabbit antibody. Immunochemistry. 1965 Dec;2(4):351–357. doi: 10.1016/0019-2791(65)90035-2. [DOI] [PubMed] [Google Scholar]
  5. Gray W. R., Dreyer W. J., Hood L. Mechanism of antibody synthesis: size differences between mouse kappa chains. Science. 1967 Jan 27;155(3761):465–467. doi: 10.1126/science.155.3761.465. [DOI] [PubMed] [Google Scholar]
  6. Hill R. L., Delaney R., Fellows R. E., Lebovitz H. E. The evolutionary origins of the immunoglobulins. Proc Natl Acad Sci U S A. 1966 Dec;56(6):1762–1769. doi: 10.1073/pnas.56.6.1762. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. INGRAM V. M. Gene evolution and the haemoglobins. Nature. 1961 Mar 4;189:704–708. doi: 10.1038/189704a0. [DOI] [PubMed] [Google Scholar]
  8. Mangalo R., Iscaki S., Raynaud M. Présence d'activité anticorps dans des préparations de chaînes légères. C R Acad Sci Hebd Seances Acad Sci D. 1966 Jul 11;263(2):204–207. [PubMed] [Google Scholar]
  9. Marchalonis J., Edelman G. M. Polypeptide chains of immunoglobulins from the smooth dogfish (Mustelus canis). Science. 1966 Dec 23;154(3756):1567–1568. doi: 10.1126/science.154.3756.1567. [DOI] [PubMed] [Google Scholar]
  10. Milstein C. Immunoglobulin kappa-chains. Comparative sequences in selected stretches of Bence-Jones proteins. Biochem J. 1966 Nov;101(2):352–368. doi: 10.1042/bj1010352. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Putnam F. W., Titani K., Whitley E., Jr Chemical structure of light chains: amino acid sequence of type K Bence-Jones proteins. Proc R Soc Lond B Biol Sci. 1966 Nov 22;166(1003):124–137. doi: 10.1098/rspb.1966.0088. [DOI] [PubMed] [Google Scholar]
  12. Singer S. J., Doolittle R. F. Antibody active sites and immunoglobulin molecules. Science. 1966 Jul 1;153(3731):13–25. doi: 10.1126/science.153.3731.13. [DOI] [PubMed] [Google Scholar]
  13. Titani K., Whitley E., Jr, Putnam F. W. Immunoglobulin structure: variation in the sequence of Bence Jones proteins. Science. 1966 Jun 10;152(3728):1513–1516. doi: 10.1126/science.152.3728.1513. [DOI] [PubMed] [Google Scholar]
  14. Titani K., Wikler M., Putnam F. W. Evolution of immunoglobulins: structural homology of kappa and lambda Bence Jones proteins. Science. 1967 Feb 17;155(3764):828–835. doi: 10.1126/science.155.3764.828. [DOI] [PubMed] [Google Scholar]

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