Abstract
ESPRE, a knowledge-based system designed to facilitate good platelet transfusion practices, is under development at the University of Minnesota Hospital and Clinic. This microcomputer based decision support system aids Blood Bank personnel in evaluating requests for platelet transfusions. Because of a direct link with the laboratory computers, most patient data need not be entered manually, but rather can be accessed directly. ESPRE uses a combination of frames and rules during its inference procedure and generates an explanation of its line of reasoning. In a preliminary comparison of the system with blood bank personnel in evaluating transfusion requests, four discrepant cases were found among fifty-eight cases evaluated.
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