Skip to main content
Proceedings of the Annual Symposium on Computer Application in Medical Care logoLink to Proceedings of the Annual Symposium on Computer Application in Medical Care
. 1988 Nov 9:261–265.

Using the ADAP Learning Algorithm to Forecast the Onset of Diabetes Mellitus

Jack W Smith, JE Everhart, WC Dickson, WC Knowler, RS Johannes
PMCID: PMC2245318

Abstract

Neural networks or connectionist models for parallel processing are not new. However, a resurgence of interest in the past half decade has occurred. In part, this is related to a better understanding of what are now referred to as hidden nodes. These algorithms are considered to be of marked value in pattern recognition problems. Because of that, we tested the ability of an early neural network model, ADAP, to forecast the onset of diabetes mellitus in a high risk population of Pima Indians. The algorithm's performance was analyzed using standard measures for clinical tests: sensitivity, specificity, and a receiver operating characteristic curve. The crossover point for sensitivity and specificity is 0.76. We are currently further examining these methods by comparing the ADAP results with those obtained from logistic regression and linear perceptron models using precisely the same training and forecasting sets. A description of the algorithm is included.

Full text

PDF
261

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bennett P. H., Burch T. A., Miller M. Diabetes mellitus in American (Pima) Indians. Lancet. 1971 Jul 17;2(7716):125–128. doi: 10.1016/s0140-6736(71)92303-8. [DOI] [PubMed] [Google Scholar]
  2. Knowler W. C., Bennett P. H., Hamman R. F., Miller M. Diabetes incidence and prevalence in Pima Indians: a 19-fold greater incidence than in Rochester, Minnesota. Am J Epidemiol. 1978 Dec;108(6):497–505. doi: 10.1093/oxfordjournals.aje.a112648. [DOI] [PubMed] [Google Scholar]
  3. Knowler W. C., Pettitt D. J., Savage P. J., Bennett P. H. Diabetes incidence in Pima indians: contributions of obesity and parental diabetes. Am J Epidemiol. 1981 Feb;113(2):144–156. doi: 10.1093/oxfordjournals.aje.a113079. [DOI] [PubMed] [Google Scholar]
  4. McNeil B. J., Hanley J. A. Statistical approaches to the analysis of receiver operating characteristic (ROC) curves. Med Decis Making. 1984;4(2):137–150. doi: 10.1177/0272989X8400400203. [DOI] [PubMed] [Google Scholar]

Articles from Proceedings of the Annual Symposium on Computer Application in Medical Care are provided here courtesy of American Medical Informatics Association

RESOURCES