Table 2.

Effects of C3H (C) and B6 (B) Alleles in Different QTLs on Carotid Lesions and Plasma Lipid Levels in the B6.apoE^−/− and C3H.apoE^−/− Intercross

Traits	Marker	BB*	BC†	CC‡	P Value
Lesion	D1Mit45	70806±71304	56184±59943	33538±40300	2.1×10−3
	D5Mit210	38895±55573	59679±62504	56884±56415	9.3×10−2
	D6Mit102	70106±71556	53846±55193	29524±42929	8.9×10−4
	D11Mit36	70233±67856	54724±58816	30107±41469	1.1×10−3
	D12Mit285	84347±76076	51338±53111	26563±33529	1.8×10−7
LDL/VLDL	D1Mit270	645±153	859±306	934±306	1.2×10−10
	D3Mit21	895±270	818±268	722±191	1.8×10−3
	D6Mit243	875±276	810±240	713±234	4.1×10−3
	D9Mit274	709±200	838±266	860±270	2.6×10−3
	D12Mit97	924±276	818±246	709±220	3.9×10−5
HDL	D1Mit406	59±28	78±34	99±47	7.1×10−8
	D2Mit263	65±33	65±26	87±42	4.8×10−5
	D17Mit244	75±38	69±34	92±42	1.3×10−3
Triglyceride	D1Mit270	120±37	168±45	175±50	2.0×10−9
	D2Mit263	134±43	163±50	160±46	2.8×10−3
	D5Mit95	141±48	148±42	172±48	1.6×10−4
	D9Mit260	132±31	163±48	166±55	3.4×10−3

Measurements are given as means ± SD. The units for these measurements are: lesion (μm² per section), LDL/VLDL, HDL cholesterol, and triglyceride (mg/dL).

^*BB, homozygous for C57BL/6 alleles,

^†CC, homozygous for C3H alleles, and

^‡BC, heterozygous for C57BL/6 and C3H alleles at the linked markers.