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. 1989 Nov;60(5):745–750. doi: 10.1038/bjc.1989.351

Primary gastrointestinal non-Hodgkin's lymphoma in a population-based registry.

R Otter 1, R Bieger 1, P M Kluin 1, J Hermans 1, R Willemze 1
PMCID: PMC2247306  PMID: 2803951

Abstract

In a population-based registry of 580 patients with non-Hodgkin's lymphoma (NHL) 54 patients had a primary gastric lymphoma, 42 an intestinal, 113 a primary extranodal lymphoma localised elsewhere than in the gastrointestinal tract and 371 a primary nodal NHL. Histological specimens were reviewed by a panel of pathologists and classified according to the Kiel classification and the International Working Formulation. The 4-year survival rates for primary gastric, intestinal, other extranodal and nodal NHL ranged from 50 to 60%; the 4-year recurrence-free survival rates were 50%, 35%, 19% and 19%, respectively. Among patients with localised intermediate-grade disease survival for those with gastric NHL was better than for those with intestinal lymphoma. Because it is population-based, our study cohort was not subjected to exclusion due to age, performance scale, etc. and therefore provides a more realistic picture of the occurrence and presentation of as well as prognosis for lymphoma in the population.

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Selected References

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  1. Aozasa K., Ueda T., Kurata A., Kim C. W., Inoue M., Matsuura N., Takeuchi T., Tsujimura T., Kadin M. E. Prognostic value of histologic and clinical factors in 56 patients with gastrointestinal lymphomas. Cancer. 1988 Jan 15;61(2):309–315. doi: 10.1002/1097-0142(19880115)61:2<309::aid-cncr2820610221>3.0.co;2-j. [DOI] [PubMed] [Google Scholar]
  2. Blackledge G., Bush H., Dodge O. G., Crowther D. A study of gastro-intestinal lymphoma. Clin Oncol. 1979 Sep;5(3):209–219. [PubMed] [Google Scholar]
  3. Brady L. W., Asbell S. O. Malignant lymphoma of the gastrointestinal tract. Erskine Memorial Lecture, 1979. Radiology. 1980 Nov;137(2):291–298. doi: 10.1148/radiology.137.2.7001537. [DOI] [PubMed] [Google Scholar]
  4. Carbone P. P., Kaplan H. S., Musshoff K., Smithers D. W., Tubiana M. Report of the Committee on Hodgkin's Disease Staging Classification. Cancer Res. 1971 Nov;31(11):1860–1861. [PubMed] [Google Scholar]
  5. Come S. E., Chabner B. A. Staging in non-Hodgkin's lymphoma: approach, results and relationship to histopathology. Clin Haematol. 1979 Oct;8(3):645–656. doi: 10.1016/s0308-2261(79)80008-9. [DOI] [PubMed] [Google Scholar]
  6. Crowther D., Rankin E. M. Staging patients with non-Hodgkin's lymphoma. Br J Haematol. 1982 Nov;52(3):357–364. doi: 10.1111/j.1365-2141.1982.tb03905.x. [DOI] [PubMed] [Google Scholar]
  7. DAWSON I. M., CORNES J. S., MORSON B. C. Primary malignant lymphoid tumours of the intestinal tract. Report of 37 cases with a study of factors influencing prognosis. Br J Surg. 1961 Jul;49:80–89. doi: 10.1002/bjs.18004921319. [DOI] [PubMed] [Google Scholar]
  8. Dragosics B., Bauer P., Radaszkiewicz T. Primary gastrointestinal non-Hodgkin's lymphomas. A retrospective clinicopathologic study of 150 cases. Cancer. 1985 Mar 1;55(5):1060–1073. doi: 10.1002/1097-0142(19850301)55:5<1060::aid-cncr2820550523>3.0.co;2-8. [DOI] [PubMed] [Google Scholar]
  9. Dworkin B., Lightdale C. J., Weingrad D. N., DeCosse J. J., Lieberman P., Filippa D. A., Sherlock P., Straus D. Primary gastric lymphoma. A review of 50 cases. Dig Dis Sci. 1982 Nov;27(11):986–992. doi: 10.1007/BF01391744. [DOI] [PubMed] [Google Scholar]
  10. Economopoulos T., Alexopoulos C., Stathakis N., Styloyannis S., Dervenoulas J., Tsousis S., Raptis S. Primary gastric lymphoma--the experience of a general hospital. Br J Cancer. 1985 Sep;52(3):391–397. doi: 10.1038/bjc.1985.206. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Freeman C., Berg J. W., Cutler S. J. Occurrence and prognosis of extranodal lymphomas. Cancer. 1972 Jan;29(1):252–260. doi: 10.1002/1097-0142(197201)29:1<252::aid-cncr2820290138>3.0.co;2-#. [DOI] [PubMed] [Google Scholar]
  12. Gospodarowicz M. K., Bush R. S., Brown T. C., Chua T. Curability of gastrointestinal lymphoma with combined surgery and radiation. Int J Radiat Oncol Biol Phys. 1983 Jan;9(1):3–9. doi: 10.1016/0360-3016(83)90200-6. [DOI] [PubMed] [Google Scholar]
  13. Green J. A., Dawson A. A., Jones P. F., Brunt P. W. The presentation of gastrointestinal lymphoma: study of a population. Br J Surg. 1979 Nov;66(11):798–801. doi: 10.1002/bjs.1800661114. [DOI] [PubMed] [Google Scholar]
  14. Haak H. L., Kluin P. M., Meyer C. J., Otter R., Stijnen T., Bieger R., van Groningen K., Kerkhofs H., Noordijk E. M., vd Sandt M. M. Population-based registration of non-Hodgkin lymphoma in the region covered by the Comprehensive Cancer Centre West. The registry of diagnosis and therapy. Neth J Med. 1986;29(4):105–110. [PubMed] [Google Scholar]
  15. Haber D. A., Mayer R. J. Primary gastrointestinal lymphoma. Semin Oncol. 1988 Apr;15(2):154–169. [PubMed] [Google Scholar]
  16. Lewin K. J., Ranchod M., Dorfman R. F. Lymphomas of the gastrointestinal tract: a study of 117 cases presenting with gastrointestinal disease. Cancer. 1978 Aug;42(2):693–707. doi: 10.1002/1097-0142(197808)42:2<693::aid-cncr2820420241>3.0.co;2-j. [DOI] [PubMed] [Google Scholar]
  17. List A. F., Greer J. P., Cousar J. C., Stein R. S., Johnson D. H., Reynolds V. H., Greco F. A., Flexner J. M., Hande K. R. Non-Hodgkin's lymphoma of the gastrointestinal tract: an analysis of clinical and pathologic features affecting outcome. J Clin Oncol. 1988 Jul;6(7):1125–1133. doi: 10.1200/JCO.1988.6.7.1125. [DOI] [PubMed] [Google Scholar]
  18. Maor M. H., Maddux B., Osborne B. M., Fuller L. M., Sullivan J. A., Nelson R. S., Martin R. G., Libshitz H. I., Velasquez W. S., Bennett R. W. Stages IE and IIE non-Hodgkin's lymphomas of the stomach. Comparison of treatment modalities. Cancer. 1984 Dec 1;54(11):2330–2337. doi: 10.1002/1097-0142(19841201)54:11<2330::aid-cncr2820541104>3.0.co;2-v. [DOI] [PubMed] [Google Scholar]
  19. Musshoff K. Klinische Stadieneinteilung der Nicht-Hodgkin-Lymphome. Strahlentherapie. 1977 Apr;153(4):218–221. [PubMed] [Google Scholar]
  20. Sheridan W. P., Medley G., Brodie G. N. Non-Hodgkin's lymphoma of the stomach: a prospective pilot study of surgery plus chemotherapy in early and advanced disease. J Clin Oncol. 1985 Apr;3(4):495–500. doi: 10.1200/JCO.1985.3.4.495. [DOI] [PubMed] [Google Scholar]
  21. Shiu M. H., Nisce L. Z., Pinna A., Straus D. J., Tome M., Filippa D. A., Lee B. J. Recent results of multimodal therapy of gastric lymphoma. Cancer. 1986 Oct 1;58(7):1389–1399. doi: 10.1002/1097-0142(19861001)58:7<1389::aid-cncr2820580702>3.0.co;2-y. [DOI] [PubMed] [Google Scholar]
  22. Thorling K. Gastric lymphomas. Clinical features, treatment and prognosis. Acta Radiol Oncol. 1984;23(2-3):193–197. doi: 10.3109/02841868409136011. [DOI] [PubMed] [Google Scholar]
  23. Warnke R. A., Gatter K. C., Falini B., Hildreth P., Woolston R. E., Pulford K., Cordell J. L., Cohen B., De Wolf-Peeters C., Mason D. Y. Diagnosis of human lymphoma with monoclonal antileukocyte antibodies. N Engl J Med. 1983 Nov 24;309(21):1275–1281. doi: 10.1056/NEJM198311243092102. [DOI] [PubMed] [Google Scholar]
  24. Weingrad D. N., Decosse J. J., Sherlock P., Straus D., Lieberman P. H., Filippa D. A. Primary gastrointestinal lymphoma: a 30-year review. Cancer. 1982 Mar 15;49(6):1258–1265. doi: 10.1002/1097-0142(19820315)49:6<1258::aid-cncr2820490630>3.0.co;2-4. [DOI] [PubMed] [Google Scholar]

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